平阳霉素致急性肺间质病变七例报告  

Treatment of peplomycin-induced acute pulmonary interstitial lesions:7 cases report

作　　者：杜剑平[1] 季楚舒[1] 章余妹[2] 杨守梅[2] 江丰收[1] 

机构地区：[1]安徽医科大学附属省立医院肿瘤内科,合肥230001 [2]安徽省肿瘤医院肿瘤内科

出　　处：《中国肿瘤临床与康复》2010年第3期255-256,259,共3页Chinese Journal of Clinical Oncology and Rehabilitation

摘　　要：目的总结7例平阳霉素致急性肺间质病变的治疗情况。方法在急性间质性肺炎渗出期大剂量地塞米松冲击,待急性渗出消散后,才逐渐减量是有效治疗的关键。结果经治7例,1例死于治疗无效,1例死于继发病变,总有效率71.4%。结论平阳霉素致肺间质性病变渗出期大剂量地塞米松冲击治疗是有效治疗的关键。Objective To summarize the treatment of 7 cases of peplomycin-induced acute pulmonary interstitial lesions.Methods High-dose dexamethasone was used to treat exudative phase of acute interstitial pneumonia until the acute exudate dissipated,then the dose of dexamethasone was gradually reduced.Results Of the 7 patients,1 died of ineffective treatment,1 died of secondary lesions,the total effective rate was 71.4%.Conclusion High-dose dexamethasone pulse therapy is the effective treatment for exudative phase of peplomycin-induced pulmonary interstial lesions.

关 键 词：平阳霉素 急性肺间质病变 地塞米松 

分 类 号：R595.3[医药卫生—内科学]