现代中药分析新进展  

Recent advance of Traditional Chinese Medicine analysis

作　　者：夏建飞[1,2] 梁琼麟[1] 罗国安[1] 

机构地区：[1]清华大学分析中心,北京100084 [2]华东理工大学药学院,上海200037

出　　处：《中国科学：化学》2010年第6期641-650,共10页SCIENTIA SINICA Chimica

基　　金：国家自然科学基金(20805026);科技部国际合作科技项目(2010DFA32420);国家科技支撑计划课题(2006BAI08B04);国家重点基础研究发展计划(2007CB714505);国家"新药创制"重大专项课题(2009ZX09311-001)资助

摘　　要：近年来中药分析领域取得了非常大的进展,主要特点有:中药分析的对象更集中于针对中医药现代化研究中的关键科学问题,提出切合实际的系统的解决方案;中药分析不再局限于提供化学分析的工具,而是将各种新方法、新技术整合使之成为解决关键科学问题的新体系;中药分析已经不再局限于分析中药的物质组成,更注重解决的是物质的组成及其功能的相关性.本文从中药信息表达模式的改变、成分研究策略的改变、分析对象的改变和药物效应分析模式的改变等四个方面对中药现代分析的进展和发展趋势进行了综述和讨论.In recent years,there has been great progress in the field of analysis of Traditional Chinese Medicine（TCM）,with the following features：the research object of TCM analysis has been beyond the common analysis technology and focused on the key scientific issues of TCM;it has been beyond the tool of chemical analysis and tried to set up new systems to solve the key issues of TCM by integrating the methods and technologies of various subjects;the analysis has been beyond the identification of the composition of TCM and paid more attention to the relationship between composition and function.Therefore,the progress and trend of modern TCM analysis is discussed and prospected in the present review paper,focusing on four aspects,namely the changes of information expression patterns,the changes of research strategies on TCM chemistry,the changes of the research objects and the changes of analysis model of pharmaceutical activity.

关 键 词：中药 信息表达 成分研究 分析对象 药物效应 

分 类 号：R284[医药卫生—中药学]