一种用于表面等离子体共振传感器的纳米多孔金膜  

A New Type of Nano-Porous Gold Membrane for Surface Plasmon Resonance Biosensor

作　　者：杨胤[1,2] 吴一辉[1] 郝鹏[1] 张志强[1,2] 

机构地区：[1]中国科学院长春光学精密机械与物理研究所,应用光学国家重点实验室,吉林长春130033 [2]中国科学院研究生院,北京100049

出　　处：《光谱学与光谱分析》2010年第7期1898-1901,共4页Spectroscopy and Spectral Analysis

基　　金：国家高技术研究发展(863计划)项目(2006AA04Z367);国家自然科学基金项目(60971025);中国科学院知识创新工程重要方向项目(KJCX2-YW-H18)资助

摘　　要：为了打破传统的表面等离子体共振(SPR)生物传感器灵敏度不高的限制,近年来纳米材料在SPR生物传感器中的运用得到广泛的研究。但是纳米材料的制备一般都比较困难而且费用高昂,这给研究带来了困难。笔者采用化学腐蚀法制备出一种纳米多孔金膜,利用扫描电子显微镜和光谱仪等测试手段对该金膜的结构和光学性质进行了分析,并将该金膜用于SPR生物传感器实验研究。结果表明,与传统的平面金膜相比,该纳米多孔金膜具有独特的局域表面等离子体共振效应。装配有该金膜的SPR生物传感器在对生物试剂的检测中灵敏度有了一定程度的提高,且该金膜的制备方法简单,成本低廉,完全可以替代传统的平面金膜使用。Nano-porous gold membrane was fabricated by chemical etching method in the present work. The structures and the unique optical properties of the membrane were studied by scanning electron microscope and spectrometer. We creatively used the nano-porous gold membrane as the sensing layer for surface plasmon resonance biosensor. The results showed that, compared to the traditional evaporated gold film, the nano-porous gold membrane has a unique effect of localized surface plasmon resonance. The sensitivity of detecting the biological agents was obviously increased by the surface plasmon resonance biosensor assembling the nano--porous gold membrane. The fabrication method of the nano-porous gold membrane is simple and low-cost, so it absolutely can replace the use of traditional evaporated gold film.

关 键 词：表面等离子体共振传感器 局域表面等离子体共振 纳米多孔金膜 灵敏度 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]