手足口病多次感染的地理流行病学研究  

Geographic epidemiological characteristics of repeated hand foot mouth disease infections in China

作　　者：闫磊[1,2] 黄晓霞[1] 王晓芳[1] 王琦[1] 阎守邕[3] 张彦平[1] 王世文[1] 

机构地区：[1]中国疾病预防控制中心病毒病预防控制所,北京100052 [2]中国现场流行病学项目 [3]中国科学院遥感应用研究所

出　　处：《中国预防医学杂志》2010年第6期548-550,共3页Chinese Preventive Medicine

基　　金："艾滋病和肝炎等重大传染病防治"科技重大专项(2008ZX10004-008;2008ZX10004-010)

摘　　要：目的揭示手足口病多次感染的发生率、人群及空间分布的特点,为手足口病的防控提供科学依据。方法利用疾病监测信息报告管理系统手足口病的个案数据,在数据库软件的支持下筛选多次感染的病例,计算发生率、分析人群的特点并遵照地理流行病学的原理与方法,揭示其空间分布的规律和特点。结果在全国2008年5月至2009年5月间发生的70多万个手足口病患儿中,有798名患两次及以上的感染,发生率约为千分之一。其空间分布多集中在我国南方(广东、广西)及手足口病病原复杂地区,全国除西藏、黑龙江等少数几个省外普遍存在。多次感染的患者中,男性多于女性,年龄多小于5岁,3岁以下儿童多为散居儿童,3岁以上儿童多为托幼机构抚育。结论手足口病的分布有明显的地域差异,且在不同年龄组与性别间也有明显的不同。地理流行病学方法是快速、直观揭示这些变化的有效手段。Objective To analyze epidemical characteristics of repeated hand foot mouth disease（HFMD）infections in China.Methods The repeated HFMD incidences were collected from National Disease Surveillance and Report System.The thematic map of the disease distribution was created with GIS software Results There were more than 700 000 cases of HFMD and 798（about 0.1% of the total cases）repeated infections occurred in China from May 2008 to may 2009.The thematic map showed that most of the repeated HFMD infections occurred in the southern China,especially in Guangdong,Guangxi and etc.,where different pathogens were involved in the disease.The repeated infections happened more frequently in male children than in females and 77.8% of the infections occurred in children below 3 years old.Conclusion The GIS method is helpful in understanding geographic distribution and other related characteristics of repeated HFMD infections.

关 键 词：手足口病 多次感染 地理流行病学 地理信息系统 

分 类 号：R181.3[医药卫生—流行病学]