血浆抑制素A在预测持续性异位妊娠中的价值  

Serum inhibin-A level as a predictor of persistent ectopic pregnancy

作　　者：李楠[1] 宋堃玲[1] 

机构地区：[1]青岛市市立医院妇科,山东266071

出　　处：《中国预防医学杂志》2010年第6期597-598,共2页Chinese Preventive Medicine

摘　　要：目的探讨血清抑制素A(inhibin-A)水平在预测腹腔镜下输卵管妊娠保守性手术后发生持续性异位妊娠(PEP)中的价值。方法采用酶联免疫吸附法(ELISA)检测持续性异位妊娠患者(PEP组)21例、非持续性异位妊娠患者(非PEP组)226例外周血清中inhibin-A、β-hCG在术前1 d及术后水平及其变化。结果①PEP组术前1 d血清inhibin-A水平明显高非PEP组(P<0.01);②以术前1 d血清inhibin-A水平≥180 ng/L为阈值,预测PEP发生的敏感度和特异度分别为0.76和0.85。结论联合监测血清inhibin-A及β-HCG可作为持续性异位妊娠的辅助诊断;对临床选择适宜的治疗方式具有指导意义。Objective To evaluate the serum inhibin-A level as a predictor of persistent ectopic pregnancy（PEP）after laparascopic salpingostomy.Methods The study had 21 PEP and 226 non-PEP women.Serum level and dynamic variation of inhibin-A and β-hCG were measured with ELISA one day before and after operation.Results The concentration of serum inhibin-A before operation was significantly higher in PEP women than that in non-PEP patients（P0.01）.The sensitivity and the specificity were 76% and 85% respectively for PEP with high concentration of serum inhibin-A before operation（180 ng/L）as a predictor.Conclusion The high concentration of inhibin-A and β-HCG could predict PEP and should be helpful in selection of an appropriate treatment.

关 键 词：抑制素A 持续性异位妊娠 人绒毛膜促性腺激素 

分 类 号：R714.22[医药卫生—妇产科学]