原癌基因致急性心肌梗死后心室重构的研究进展  

The research progress of proto-oncogene induced ventricular remodeling after acute myocardial infarction

作　　者：文婷婷[1] 陈萍[1] 

机构地区：[1]重庆医科大学附属第一医院麻醉科,400016

出　　处：《国际麻醉学与复苏杂志》2010年第3期248-250,257,共4页International Journal of Anesthesiology and Resuscitation

摘　　要：急性心肌梗（acute myocardial infarction，AMI）后心室重构是临床上常见的进行性发展的病理生理过程，而重构的程度与患者心功能和预后密切相关。目前，原癌基因引起AMI后心室重构的作用机制已逐渐被人们认识，而通过对原癌基因的调控为心室重构的防治提供了新的思路。Ventricular remodeling after acute myocardial infarction is a common physiopathologic process in clinics, and the extent of ventricular remodeling is closely related to cardiac function and prognosis of patients. At present, the mechanism of Proto- oncogene induced ventricular remodeling after acute myocardial infarction has been recognized. Therefore , regulating the expression of Proto-oncogene provide us a new therapeutic way of ventricular remodeling.

关 键 词：急性心肌梗死 原癌基因 心室重构 

分 类 号：R542.22[医药卫生—心血管疾病]