化工原料中甲缩醛的顶空气相色谱-质谱联用测定方法研究  

Research on method for determination of methylal in chemical raw materials by head space GC-MS

作　　者：张英[1] 蔡志斌[1] 刘丽[1] 

机构地区：[1]广东省深圳市龙岗区疾病预防控制中心,广东深圳518172

出　　处：《中国卫生检验杂志》2010年第6期1341-1342,1346,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:建立化工原料中甲缩醛的顶空气相色谱-质谱联用测定方法。方法:采用顶空进样,HP-5毛细色谱柱分离,顶空温度为60℃,平衡时间30 min,气相色谱-质谱联用仪测定。结果:甲缩醛浓度在0μg～200μg内呈良好线性关系,相关系数0.9997,最低检出限0.16 mg/kg,相对标准偏差1.7%～5.8%(n=6),回收率为80%～104.5%。结论:该方法快速、简单、准确、灵敏度高,可用于化工原料中甲缩醛含量测定。Objective：To establish a method for methylal in the chemical raw materials by head space GC-MS.Methods：The head space temprature was 60℃and equilibrium time was 30 min,HP-5 capillary column was selected for separating Head Space GC-MS,and finally detected by mass detector.Results：The good linear range of method was 0 μg to 200 μg（r=0.9997）with the correlation coeffivient of 0.9997,and the limit concentration in air was 0.16 mg/kg with the average relative standard deviation between 1.7%～5.8%（n=6）,with average recoveries ranged from 80% to 104.5%.Conclusion：This method is sensitive,accurate and precise for rapid determiantion of methylal from chemical raw materials.It is suitable for determining methylal in the chemical raw materials.

关 键 词：甲缩醛 顶空气相色谱-质谱联用法 化工原料 

分 类 号：O657.71[理学—分析化学]