TRIVEXTMⅡ旋切系统在下肢静脉性皮肤溃疡治疗中的应用研究  

Application of TRIVEXTM Ⅱ Potary System in the Treatment of Venous Ulcer in Lower Extremity

作　　者：李鹏[1] 杨镛[1] 杨国凯[1] 何晓明[1] 陆平[1] 马震寰[1] 

机构地区：[1]昆明医学院第四附属医院血管外科,云南昆明650021

出　　处：《昆明医学院学报》2010年第6期70-73,共4页Journal of Kunming Medical College

基　　金：云南省自然科学基金资助项目(2008CD205);云南省中青年学术与技术带头后备人才资助项目(2008PY044)

摘　　要：目的探讨TRIVEXTMⅡ旋切系统用于下肢静脉性皮肤溃疡治疗的临床依据.方法条件性选择下肢静脉性皮肤溃疡200例200条下肢,其中,TRIVEXTMⅡ系统治疗组(A组)120例120条下肢,经皮缝扎术组(B组)80例80条下肢,于术后5d、20d、120d及360d时分别观察两组皮肤的感染率、坏死率、色素减退率、创面收缩率、溃疡愈合率及溃疡复发率等6项临床指标.结果术后5d,皮肤感染率和皮肤坏死率A组低于B组(P<0.05);术后20d创面收缩率与色素减退率A组较B组显著降低(P<0.05);术后120d,溃疡愈合率A组与B组相近(P>0.05);术后12个月溃疡复发率A组低于B组(P<0.05).结论 TRIVEXTMⅡ旋切系统可有效促进下肢静脉性皮肤溃疡的愈合,并在减轻皮肤感染及皮肤再损伤方面具有较强优势.Objective To investigate the evidence of clinical application of TRIVEXTMII potary system in the treatment of venous ulcer in the lower extremity.Methods The clinical data of 200 cases involving 200 legs with venous ulcer in the lower extremity,who accepted the TRIVEXTM Ⅱ potary system or the percutum transfixion surgical treatment from October 2005 to May 2009,were analyzed and studied.200 cases were randomly divided into group A and group B,In the group A,there were 120 cases involving 120 legs treated with TRIVEXTMII potary system,in the group B,80 cases involving 80 legs were treated with percutem transfixion. The skin infection rate,necrosis rate,shrinkage rate of wound area,skin depigmentation rate,ulcer healing rate and ulcer recurrence rate were observed at 5 day,20 day,120 day and 360 day after the operation respectively. Results The incidence of skin infection and skin necrosis was significantly lower in group A than that in group B at 5 day after operation （P0.05）.The rate of shrinkage of wound area and skin depigmentation was significantly different between group A and group B at 20 day （P0.05）.The ulcer healing rate was not significantly different between group A and group B at 120 day （P0.05）.The ulcer recurrence rate was arkably lower in group A than that in group B at 360 day （P0.05）.Conclusions TRIVEXTM Ⅱ potary system can efficiently promote the healing of venous ulcer in the lower extremity,and at the same time it has a ascendancy in reducing the incidence of skin infection and skin reinjury.

关 键 词：下肢 静脉 溃疡 治疗 疗效 

分 类 号：R619[医药卫生—外科学] R654.4[医药卫生—临床医学]