COPD患者机械通气两种撤机方法的临床随机对照研究  

Comparison of two weaning methods for patients with chronic obstructive pulmonary disease

作　　者：李超[1] 燕存子[1] 王在义[1] 

机构地区：[1]新疆医科大学第一附属医院呼吸科,新疆乌鲁木齐830011

出　　处：《新疆医科大学学报》2010年第5期561-564,共4页Journal of Xinjiang Medical University

摘　　要：目的评价同步间隙指令通气(SIMV)和压力支持通气(PSV)对慢性阻塞性肺疾病(COPD)机械通气患者撤机、拔管的优劣。方法采用随机对照试验,将符合入选标准的32例COPD机械通气的患者分为两组,同步间歇指令通气(SIMV)组和压力支持通气(PSV)组。观察两组撤机前后血气变化、撤机成功率、撤机失败率和再插管率,对比两种撤机方法的优劣性和临床实用性。结果参加试验的32例患者均完成试验,无失访和提前退出者。SIMV组和PSV组患者一般情况差异无统计学意义(P>0.05);两组撤机成功率、撤机失败率、重新插管率均无统计学差异(P>0.05);两组撤机时间有统计学差异(P<0.05)。结论同步间歇指令通气和压力支持通气在COPD机械通气患者撤机成功率、拔管率均高,均可较好地应用于临床。Objectives To evaluate the effects of spontaneous intermittent mandatory ventilation（SIMV） and pressure support ventilation（PSV） in the weaning process for patients with chronic obstructive pulmonary disease.Methods Thirty-two patients with COPD meeting the conditions of the trial were randomly divided into two groups（n=16）,PSV group and SIMV group.We observed the changes of blood gas before and after the weaning and the ratio of weaning failure,weaning succeed and reintubation.Then we compared the effects and clinical utility of these two methods.Results The thirty-two patients all completed the trial.There was no significant differene between the two groups in basical conditions,the ratio of failure,succeed and reintubation of weaning.And the two groups have highly ratio in successful weaning.Duration of weaning in two groups was obvionsly different（P0.05）.Conclusion The two methods both have high ratio of weaning and extubation,which all can be applied widely to clinical.

关 键 词：慢性阻塞性肺疾病 机械通气 撤机 

分 类 号：R563[医药卫生—呼吸系统]