老年糖尿病患者红细胞膜Na^+-K^+-ATP酶活性及临床意义  

Clinical significance of Na + K + ATPase in the membrane of red blood cell in aged diabetic patients

作　　者：王桂侠[1] 张兵华 郝守才[1] 李广仁[2,3] 

机构地区：[1]白求恩医科大学第一临床学院内分泌科 [2]白求恩医科大学第一临床学院神经内科 [3]海南武警总队医院

出　　处：《中国老年学杂志》1999年第2期99-100,共2页Chinese Journal of Gerontology

摘　　要：通过测定老年糖尿病患者红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶活性，发现糖尿病患者红细胞膜Ｎａ＋－Ｋ＋－ＡＴＰ酶活性明显低于对照组，血糖与Ｎａ＋－Ｋ＋－ＡＴＰ酶活性呈负相关（ｒ＝－０．６５６）。糖尿病伴神经病变患者神经传导速度明显减慢，Ｎａ＋－Ｋ＋－ＡＴＰ酶活性倾向低于不伴神经病变者。Erythrocyte Na + K + ATPase activity were mesured in a group of aged diabetic patients.The result showed that erythrocyte Na + K + ATPase activity was significantly reduced in aged diabetic patients as compared with age matched control subjects.Blood glucose level was negatively correlated with Na + K + ATPase activity.And motor nerve conduction velocity(MNCV) was significantly decreased and Na + K + ATPase activity tended to reduce in the diabetic patients with neuropathy as compared with the patients without neruopathy.\;

关 键 词：糖尿病 NA^+-K^+-ATP酶 红细胞 老年人 

分 类 号：R587.1[医药卫生—内分泌]