囊素肽对禽流感(H9N2)油乳剂灭活疫苗免疫效果的影响  

Effects of bursin on avian influenza(H9N2) oil adjuvant inactivated vaccine

作　　者：许家荣[1] 陈闻[1] 李臻兴 尚月丽[1] 许俊才[1] 

机构地区：[1]南京农业大学动物医学院,江苏南京210095 [2]江西省种鸡场,江西南昌330200

出　　处：《浙江农业学报》2010年第3期298-301,共4页Acta Agriculturae Zhejiangensis

基　　金：江苏高校高新技术产业发展项目(JHB0510);江苏省农业三项工程[sx(2008)108];公益性行业(农业)科研专项(子专题)(200803020)

摘　　要：为研究囊素肽对禽流感(H9N2)油乳剂灭活疫苗免疫效果的影响,将200只鸡分为疫苗组、疫苗+囊素组、囊素组和对照组,每组50只。从13日龄起每7 d测定其法氏囊指数、禽流感(H9)HI抗体水平。结果表明:囊素肽能提高禽流感(H9N2)油乳剂灭活疫苗免疫后的抗体水平,并延长高水平抗体的维持期,能显著地促进法氏囊的生长发育。In order to determine the immune regulatory effect of bursin on avian influenza（H9N2） vaccine,two hundred 13-day-old chicken were randomly divided into four groups.One was for the control,the others for vaccine,vaccine plus bursin and bursin treatments respectively.The change of average index of bursa of fabricius and spleen and serum antibody titer in chicken were examined by means of hemagglutination inhibition test every 7 days from the 13th day after treatment.The results showed that bursin could enhance chicken serum antibody titer on avian influenza（H9N2） oil adjuvant inactivated vaccine and develop bursa of fabricius significantly.Bursin also could prolong the maintenance of high serum antibody titer in chicken.It was suggested that bursin could improve immune effects of avian influenza（H9N2） oil adjuvant inactivated vaccine in chicken.

关 键 词：囊素肽 禽流感(H9N2)油乳剂灭活疫苗 法氏囊指数 禽流感(H9N2)病毒HI抗体水平 

分 类 号：S852.5[农业科学—基础兽医学]