五倍子水煎剂对老龄小鼠抗衰老作用的实验研究  

Experimental study in anti-aging effect of Rhus Chinensis Mill decoction on old mice

作　　者：李怀荆[1] 毛金军[1] 崔凤起[1] 王淑湘 张明远 赵锦程[1] 

机构地区：[1]佳木斯大学医学院药理教研室

出　　处：《黑龙江医药科学》1999年第1期12-13,共2页Heilongjiang Medicine and Pharmacy

摘　　要：中药五倍子水煎剂给予老龄小鼠灌胃（5g／kg），每日1次，连用4周．采用邻苯三酚自氧化法、DTNB和TBA比色法测定红细胞超氧化物歧化酶（SOD）活性，全血谷胱甘肽过氧化物酶（GSH－Px）活力和红细胞中及血浆中MDA含量．结果表明，五倍子水煎剂能显著增强老龄小鼠红细胞SOD活性、全血GSH－Px的活力，而且可显著降低红细胞和血浆中MDA含量，故具有延缓衰老作用．Rush Chinensis Mill decoction was poured into the stomache of old mice for four weeks. The activity of SOD in erythrocyte and GSH-Px in blood was more significantly increased than that of the control group(P<0.05), while the level of MDA in erythrocyte and plasma was decreased greatly (P<0.01). The results showed that Rush Chinensis Mill has some anti-aging function.

关 键 词：五倍子 超氧化物歧化酶 GSH-PX 丙二醛 

分 类 号：R282.710.5[医药卫生—中药学] R285.5[医药卫生—中医学]