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作 者:陈亦兰[1] 陈绍红[2] 范华莹[1] 梁军成[1] 孙莉[1] 白晓菊[3] 张德芹[4] 沈黎阳[1] 徐国柱[1] 时杰[1] 邓艳萍[1] 高学敏[2]
机构地区:[1]北京大学中国药物依赖性研究所,北京100191 [2]北京中医药大学,北京100029 [3]国家药典委员会,北京100061 [4]天津中医药大学,天津300193
出 处:《中国药物依赖性杂志》2010年第3期210-216,共7页Chinese Journal of Drug Dependence
基 金:国家科技支撑计划项目(2008BAI49B01)资助
摘 要:目的:对《阿片类药物成瘾急性戒断期中医证候评定量表》进行信度、效度评定,并针对量表的不足之处提出修改意见。方法:利用中药戒毒临床研究中使用该量表进行戒断症状评分时收集到的数据,对《阿片类药物成瘾急性戒断期中医证候评定量表》进行信度、效度评定。然后根据因子分析和条目筛选结果提出量表修改意见,最后完成修改后量表的信度、效度评定。同质性信度的检测方法为Cronbachα系数,结构效度评定采用主成分法配合最大正交旋转。条目筛选方法包括:重要性评分法、离散趋势法、相关系数法和专家评定法。结果:原量表中7个条目的原有分层与因子分析结果不一致。结合专家意见对量表结构进行调整后,得到21个条目的新量表。根据条目筛选结果,建议删除重要性、敏感性、代表性均较差的3个条目。对修改后量表进行信度、效度评定,结果显示新量表较原量表具有更好的结构效度,条目归类也更为合理。总量表、毒瘀互阻证、寒证和热证因子层面的Cronbachα系数分别为0.740、0.676、0.420、0.681。结论:原量表的结构效度和部分因子的内部一致性较差,依据修改意见调整后得到的新量表具有更好的结构效度,部分因子的信度值提高,调整后的量表具有较好的信度和效度。Objective:To evaluate the validity and reliability of the TCM Syndrome Rating Scale for Opioid Addiction in Acute Withdrawal Phase and propose amendments to the inadequacies of the scale.Methods:We used data collected from clinical research of TCM treatment on opioid-dependence to evaluate the validity and reliability of the original scale,proposed amendments according to the results of factor analysis and item selection and analyzed the construct validity and homogeneity reliability of the revised scale.The extraction and rotation method of construct validity were principal components and varimax,respectively.Model of homogeneity reliability was Cronbach's α coefficient.Four item selection methods were:the significance evaluation,discrete trend method,correlation coefficient method and Delphi method.Results:The original classification of 7 items in the original scale was inconsistent with factor analysis results.The number of items of the original scale was adjusted to 21 in the new scale based on expert opinion.According to the results of item selection,3 items were proposed to be deleted since little importance in every aspect.The revised scale possesses better construct validity through factor analysis,items in the same factors share common characteristics and can be reasonably explained.Cronbach's α coefficient of the revised scale,poison-blood stasis syndromes factor,cold syndromes factor and heat syndromes factor were 0.740,0.676,0.420,0.681,respectively.Conclusion:The construct validity and homogeneity reliability of original scale was poor.After being revised,the new scale has better construct validity and Cronbach's α coefficient.
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