芥酸甲酯氧化制备十三烷二酸  

Preparation of brassylic acid by oxidation of methyl erucate

作　　者：耿炜[1] 邓东顺[1] 章连众[1] 乔冰帮[1] 计建炳[1] 

机构地区：[1]浙江工业大学化学工程与材料学院,浙江杭州310014

出　　处：《化工进展》2010年第7期1320-1323,1329,共5页Chemical Industry and Engineering Progress

基　　金：浙江省科技厅重点项目(2007C21126)

摘　　要：提出了一条芥酸甲酯氧化制备十三烷二酸的新工艺路线:以过氧化氢和氧气为氧化剂,芥酸甲酯经烯键环氧化、环氧水解、邻二醇氧化裂解等反应制备十三烷二酸。着重研究了烯键环氧化和环氧水解反应中,影响烯键环氧化反应收率和中间产物羟基值的条件参数。结果表明:含邻二醇的中间产物的羟基值越高,十三烷二酸的总体收率越高;采用新工艺路线,十三烷二酸的总收率达到70.3%,具有工业化应用前景。A new process was proposed for preparation of brassylic acid by oxidation of methyl erucate.Brassylic acid was obtained through C=C bond epoxidation,epoxide hydrolysis and oxidative cleavage of vicinal diol from methyl erucate using hydrogen peroxide and oxygen as oxidants.Parameters for improving the epoxidation yield and the hydroxyl value of vicinal diol were investigated.The experimental results indicated that the larger the hydroxyl value of vicinal diol,the higher the total yield of brassylic acid,with the best yield of 70.3%.This process can be expected to have a good prospect for industrial application.

关 键 词：芥酸甲酯 氧化裂解 十三烷二酸 邻二醇 

分 类 号：O623.613[理学—有机化学]