艾滋病筛查实验室检测准确性的变化趋势  

The trend of accuracy change in HIV laboratory screening tests

作　　者：周广军[1] 郝钦芳[1] 马雪平[1] 张丽萍[1] 王贝晗[1] 王莉[1] 杨晓莉[1] 

机构地区：[1]武警总医院检验科,北京100039

出　　处：《中国艾滋病性病》2010年第3期303-304,333,共3页Chinese Journal of Aids & STD

基　　金：卫生部艾滋病防治应用性研究项目资助( WA-2006-07)~~

摘　　要：目的回顾性评价艾滋病实验室筛查检测准确性的变化规律。方法对武警总医院10年的艾滋病病毒(HIV)抗体检测数据进行回顾性分析。结果 1999-2008年共检测HIV抗体90289人次,其中筛查阳性412人次,复检阳性54例,经过确认阳性19例,阴性14例,不确定21例;人群HIV抗体阳性率为0.03%,HIV抗体不确定发生率为0.03%,其复检效率为86.9%,确认效率为61.1%。HIV抗体筛查阳性率由2002年0.79%下降到2008年0.19%,首次筛查阳性的真阳性率逐年上升,由2004年3.7%上升到2008年15.4%,筛查阳性的复检阳性率由2004年7.4%上升到2008年38.5%,复检效率由2002年100.0%下降到2008年61.5%。结论艾滋病实验室HIV抗体筛查准确性10年内提高了近4倍。Objective To evaluate the trends of accuracy change in HIV laboratory screening tests by retrospectively reviewing data collected in the past decade. Methods Data of HIV antibody testing collected from the General Hospital of the People＇s Armed Forces between 1999 and 2008 were analyzed in a retrospective way. Results Among 90 289 samples of HIV antibody tests,412 were antibody positive,of which 54 were retested as positive,19 were validated as positive,14 as negative and 21 as indefinite. The HIV antibody positive rate of the reviewed samples was 0.03%,their indefinite rate was 0.03%,their retesting rate was 86.9% and their rate of validation was 61.1%. In general,the HIV antibody positive rate dropped from 0.79% in 2002 to 0.19% in 2008,while the true positive rate at the first screening test increased from 3.7% in 2004 to 15.4% in 2008,the retested positive rate rose from 7.4% in 2004 to 38.5% in 2008,and the rate of retesting dropped from 100% in 2002 to 61.5% in 2008. Conclusion The accuracy of HIV laboratory antibody tests increased by 4 folds in the past decade.

关 键 词：艾滋病病毒抗体 筛查 准确性 

分 类 号：R512.91[医药卫生—内科学]