哈尔滨市艾滋病病人高效抗反转录病毒治疗效果评价  

Efficacy evaluation of highly active anti-retroviral therapy in AIDS patients in Harbin

作　　者：刘婷[1] 钟敏[2,3] 张锋镝[3] 刘岩琳[1] 王健[1] 王滨有[2] 王福祥[3] 

机构地区：[1]哈尔滨市疾病预防控制中心,黑龙江哈尔滨150056 [2]哈尔滨医科大学流行病学教研室,黑龙江哈尔滨150081 [3]哈尔滨医科大学附属第一医院感染科,黑龙江哈尔滨150001

出　　处：《中国艾滋病性病》2010年第3期305-306,318,共3页Chinese Journal of Aids & STD

基　　金：中国博士后科学基金(20060390238);黑龙江省政府博士后启动基金(LRB-05 -263);黑龙江省教育厅基金(11531162);哈尔滨科技创新人才研究专项资金项目(2010RFQQS088)~~

摘　　要：目的探讨哈尔滨市艾滋病(AIDS)病人的高效抗反转录病毒治疗(HAART)效果与不良反应。方法应用国家免费提供的抗病毒治疗药品,对符合治疗条件的HIV/AIDS病人进行规范抗病毒治疗,并检测病人的CD4+T淋巴细胞计数与病毒载量。结果 HAART开始12个月后,病人CD4+T淋巴细胞计数平均增长(241.61±148.02)个/μl,病毒载量均低于检测下限。结论抗病毒治疗效果显著,能够实现部分免疫重建,但也存在较多的不良反应。Objective To evaluate the efficacy and side effects of highly active antiretroviral therapy （HAART） in AIDS patients in Harbin. Methods Standard antiretroviral drugs were free provided for the treatment of people living with HIV/ AIDS,and CD＋4T lymphocyte counts and HIV viral loads were detected. Results In the first year of HAART,CD＋4T lymphocyte counts increased by 241.61±148.02/μl on average. And HIV viral loads were below the minimum level. Conclusions Significant therapeutic efficacy and immune restoration are observed in advanced AIDS patients receiving HAART,but severe side effects are also present,so close clinical monitoring is essential.

关 键 词：艾滋病 高效抗反转录病毒治疗 CD4+T淋巴细胞 病毒载量 

分 类 号：R512.91[医药卫生—内科学]