两种巴氏涂片法在宫颈病变筛查中的比较分析  

Comparative analysis of modified Pap test and conventional Pap test in cervical cancer screening

作　　者：蔡虹[1] 郭利鸿 关婷[1] 

机构地区：[1]深圳市计划生育服务中心,广东深圳518028

出　　处：《检验医学与临床》2010年第12期1194-1195,1197,共3页Laboratory Medicine and Clinic

摘　　要：目的分析比较改良巴氏法及传统巴氏法在宫颈病变筛查中的作用。方法分析2006年10223例传统巴氏法及2007年9436例改良巴氏法的宫颈涂片结果 ,对两种方法的标本满意率及宫颈病变的阳性检出率进行分析,并对两种方法与组织病理学的符合率进行比较。结果改良巴氏法的标本满意率明显高于传统巴氏法差异有统计学意义(P<0.05),对非典型鳞状细胞(ASCUS)及其以上病变的检出率比较,两种方法差异有统计学意义(P<0.05)。以阴道镜下组织病理学活检为金标准,传统巴氏法与改良巴氏法对低度鳞状上皮内病变(LSIL)和高度鳞状上皮内病变(HSIL)的诊断符合率差异无统计学意义(P>0.5)。结论改良巴氏法明显提高了标本的满意率及病变的阳性检出率。Objective To compare and analyze the efficacy of using modified Pap test and conventional Pap test in cervical cancer screening.Methods Cytologic results of 10223 conventional Pap smears in 2007 and 9436 modified Pap smears in 2008 were retrieved for this study.The adequacy of the specimens and the detection rate of cervical abnormalities produced by these two techniques were analyzed,and the degrees of concordance with histological diagnoses between the two tests were also compared.Results The proportion of satisfactory smear on specimen adequacy was higher in modified Pap test than in conventional Pap test（P〈0.05）,and the detection rates for the diagnosis of ASCUS or worse were also higher in modified Pap test（P〈0.05）.With the diagnosis of colposcopic-directed biopsy as the gold standard,the diagnoses of LSIL and HSIL between the two tests were not statistically different（P〉0.05）.Conclusion Modified Pap test can increase the percentage of satisfactory smears and the detection rate of cervical abnormalities; hence,it is devoted for every worker in cytology to take great concern on the Pap smears.

关 键 词：改良巴氏涂片 检出率 宫颈病变 筛查 

分 类 号：R446.1[医药卫生—诊断学] R737.33[医药卫生—临床医学]