网状纤维在实验性肝纤维化中的动态变化  

Dynamic Changes of Reticular Fibers in Experimental Hepatic Fibrosis

作　　者：王昆[1] 吴红[1] 黄高[1] 王瑶瑶[1] 周寒[1] 

机构地区：[1]贵阳中医学院,贵州贵阳550002

出　　处：《辽宁医学院学报》2010年第3期197-198,I0001,I0002,共4页Journal of Liaoning Medical University (LNMU) Bimonthly

摘　　要：目的观察四氯化碳(CCl4)致肝纤维化小鼠网状纤维的动态变化。方法采用注射CCl4复制小鼠肝纤维化模型。结果模型组见大量黑色条索的网状纤维,形成假小叶。结论实验第3周模型组基本无网状纤维出现,6周网状纤维开始出现但量不多,9周网状纤维明显增多,并分割肝小叶,12周可见大量的网状纤维,并形成假小叶。Objective It observes the changes of reticular fiber in hepatic fibrosis rats caused by CCl4.Methods The animal mode of hepatic fibrosis was made with CCl4 injection into rats.Results The result shows that the animal mode of hepatic fibrosis has a lot of black reticular fiber and form pscudolobule.Conclusions The sufferer group has not reticular fiber in the third week.Reticular fiber has been seen but not a lot in the sixth week.It-s obvious that reticular fiber increased and cut apart hepatic lobule in the ninth week.A lot of reticular fiber has been seen and formed pscudolobule in the twelfth week.

关 键 词：肝纤维化 网状纤维 动态 

分 类 号：Q954[生物学—动物学]