优甲乐治疗早产儿暂时性低甲状腺素血症30例临床观察及护理  

Clinical observation and nursing care in the treatment of 30 premature infants with transient hypothyroxinaemia with Euthyrox

作　　者：孙献梅[1] 任香娣[1] 董爱兰[1] 

机构地区：[1]山东大学附属省立医院,山东济南250021

出　　处：《齐鲁护理杂志》2010年第6期10-12,共3页Journal of Qilu Nursing

摘　　要：目的:探讨补充优甲乐对早产儿暂时性低甲状腺素血症的疗效,为早产儿治疗及护理提供临床依据。方法:对30例早产儿补充优甲乐,采用电化学发光法检测早产儿及足月儿甲状腺激素水平。足月儿与B组患儿在生后3d测行为反射,两周后测定所有早产儿及同日龄足月儿行为反射。结果:优甲乐治疗组血清FT3、FT4高于对照组,有显著性差异(P<0.01)。优甲乐治疗组患儿行为反射得分治疗组高于对照组,差别显著有统计学意义(P<0.01)。结论:补充甲状腺素后可使早产儿血清FT3、FT4浓度明显升高,尤其FT3升高更显著,但对TSH影响不明显。对≤34W早产儿更有必要补充甲状腺素。补充甲状腺素组早产儿行为反射评分提高较未补充组明显,提示对早产儿尤其小早产儿补充甲状腺素治疗有助于其神经系统的发育。Objective ： To discuss the effectiveness of supplement therapy with euthyrox in the treatment of transient hypothyroxinaemia in preterm infants in order to provide clinical basis for the treatment and nursing care. Methods ： Supplement therapy with euthyrox was given to 30 preterm infants and electrochemiluminescence assay was used to detect thyroid hormone levels respectively in preterm infants and full - term infants. Behavioral reflex of full - term infants and preterm infants in group B was measured in 3 days after birth. Two weeks later, the behavioral reflex of all preterm infants and the full - term infants born on the same day was measured. Results： The levels of serum FT3 , FT4 were higher in the treatment group than that in the control group and there were significant differences （ P 〈 0.01 ） ; the scores of behavioral reflex of preterm infants in the treatment group were higher than that in the control group （ P 〈 0.01 ）. Conclusion： The supplement of thyroxine can significantly raise the levels of serum FT3 and FT4 of preterm infants and FT3 in particular, but no significant effect on the TSH. The preterm infants ≤ 34 weeks should necessarily be given thyroxine. The scores of behavioral reflex of the preterm infants who were treated with thyroxine were obviously higher, which suggests that supplement of thyroxine benefits to the development of nervous system of premature infants.

关 键 词：早产儿 暂时性低甲状腺素血症 甲状腺素 行为反射评分 

分 类 号：R473.72[医药卫生—护理学]