梅毒孕妇的抗梅毒治疗对先天性梅毒患儿病情及预后的影响  

Effect of anti-syphilis therapy during pregnancy on neonates with congenital syphilis

作　　者：尹虹[1] 苏卫东[2] 

机构地区：[1]温州市第二人民医院预防保健科,325000 [2]温州市第二人民医院新生儿科

出　　处：《浙江医学》2010年第6期856-857,共2页Zhejiang Medical Journal

摘　　要：目的 研究梅毒孕妇的抗梅毒治疗与先天性梅毒患儿病情及预后间的关系,以提高先天性梅毒患儿的治疗水平并改善预后.方法 65例先天性梅毒新生儿按照孕期是否接受正规抗梅毒治疗分为正规抗梅毒治疗组（A组）及未接受治疗或治疗不正规组（B组）,比较两组患儿的器官受累发生情况及预后.结果 A组中早产儿及低出生体重儿的发生率明显低于B组（P〈0.01）,A组器官受累的发生率明显低于B组（P〈0.05）,治愈好转率明显高于B组（P〈0.05）.结论 梅毒孕妇的抗梅毒治疗能减轻先天性梅毒患儿的病情、改善患儿预后.Objective To investigate the effect of anti-syphilis therapy during pregnancy on neonates with congenital syphilis. Methods Sixty five neonates with congenital syphilis were divided into 2 groups, in group A the mothers received regular anti-syphilis therapy during pregnancy and in group B the mothers receive irregular anti-syphilis therapy or no therapy. The organs involved and the prognosis of 2 groups were compared. Results The incidence of premature infants and low weight infants in group A was significantly lower than that in group B （P 〈 0.01 ）. The incidence of organs involved was lower and the cure rate was higher in group A than those in group B （P 〈0.05）. Conclusion Anti-syphilis therapy during pregnancy can alleviate the pathogenetic conditions of congenital syphilis in neonates and improve their prognosis.

关 键 词：梅毒 孕妇 新生儿 预后梅毒 孕妇 新生儿 预后 

分 类 号：R759.15[医药卫生—皮肤病学与性病学]