养血通络片质量标准研究  

Quality Standard for Yangxue Tongluo Tablets

作　　者：陈华[1] 何锦钧[1] 

机构地区：[1]广东省佛山市中医院,广东佛山528000

出　　处：《中国药业》2010年第12期39-40,共2页China Pharmaceuticals

摘　　要：目的建立养血通络片的质量控制方法。方法采用薄层色谱(TLC)法对制剂中五指毛桃、何首乌和威灵仙进行定性鉴别;采用高效液相色谱(HPLC)法对制剂中主要成分表儿茶素进行含量测定。结果薄层色谱图中斑点清晰,阴性对照品溶液无干扰。HPLC法精密度、重现性良好,表儿茶素进样量在0.0408～1.02μg范围内与峰面积呈良好线性关系(r=0.9998),加样回收率为99.21%,RSD为1.09%(n=6)。结论该法可有效控制养血通络片的质量。Objective To establish the quality standard for Yangxue Tongluo Tablets.Methods Radix Fici Hirtae and Radix Polygoni Multiflori and Clematis Chinensis Osbek were identified by TLC.The contents of epicatechin in Yangxue Tongluo Tablets were determined by HPLC.Results The developed TLC spots were fairly and simply identica1.The HPLC method was accurate and reproducible.Epicatechin showed the good linear relationship at the range of 0.040 8-1.02 μg（r = 0.999 8）.The recovery rate was 99.21% and RSD was 1.09%.Conclusion This method can be used for the quality control of Yangxue Tongluo Tablets effectively.

关 键 词：养血通络片 薄层色谱法 表儿茶素 高效液相色谱法 

分 类 号：R284.1[医药卫生—中药学] R286.0[医药卫生—中医学]