旋转磁场对人红细胞膜ATP酶的影响  

Effect of Rotary Magnetic Field （RMF） on the ATP Enzyme of Human Red Cell

作　　者：陈晨[1,2] 郭国祯[2] 谢学军[2] 夏爱军[1] 周艳[2] 郭燕[2] 刘海强[2] 穆士杰[1] 

机构地区：[1]解放军第四军医大学西京医院输血科,西安710032 [2]解放军第四军医大学军事预防医学系放射医学教研室,西安710032

出　　处：《现代检验医学杂志》2010年第3期65-66,70,共3页Journal of Modern Laboratory Medicine

基　　金：解放军第四军医大学军事预防医学系军事医学科研基金资助项目（XJ200604）,国家863计划项目（2002AA832033）.

摘　　要：目的研究旋转磁场照射后对人红细胞Na^＋-K^＋-ATP酶与Ca^2＋-Mg^2＋-ATP酶的影响，探讨旋转磁场照射是否可以改善红细胞膜的状态，提高红细胞的抗损伤能力。方法抽取10名健康志愿者静脉血，每份血均分成3份，其中2份在强度为0．6T，暴磁2h条件下照射，分剐检测照射前及照射后1，2h后Na^＋-K^＋-ATP酶与Ca^＋-Mg^2＋-ATP酶的活力。结果照射后1h红细胞膜Na^＋-K^＋-ATP酶活力由照射前的0．449±0．048μmol pi／mg pro．h升高为0．734± 0．042μmol pi／mg pro．h，Ca^2＋-Mg^2＋-ATP酶的活力由照射前的1．061±0．101μmol pi／mg pro．h升高为1．605±0．055μmol pi／mg pro．h，照射后2h红细胞膜Na^＋-K＋-ATP酶活力升高为0．738±0．056μmol pi／mg pro．h，Ca^2＋-Mg^2＋-ATP酶的活力升高为1．603±0．058μmol pi／mg pro．h。与未照射红细胞相比，照射后1，2h红细胞膜Na^＋-K^＋-ATP酶与Ca^2＋-Mg^2＋-ATP酶的活力显著升高（P〈0．05）。结论旋转磁场照射能提高红细胞ATP酶活力，改善红细胞膜的代谢，在红细胞系统中具有兴奋效应。Objective To investigate the effect of rotary magnetic field （RMF） on the ATP enzyme of human red blood cell. Methods The experiment was divided into three groups. They were control group, 1 hour after magnetic treatment group and 2 hour after magnetic treatment group. Ten blood samples were obtained from ten healthy donors. Each was divided into three parts equally. Two of which were treated with RMF for 2 hours （magnetic intensity： 0. 6 T, frequency： 7.83 Hz）. The Na^＋-K^＋-ATP enzyme and the Ca^2＋-Mg^2＋-ATP enzyme were detected before and after RMF exposure. Results Both the activity of the Na^＋-K^＋-ATP enzyme and the Ca^2＋-Mg^2＋-ATP enzyme of the red blood cells increased after RMF exposure. Conclusion Exposed to RMF can increase the activity of ATP enzyme of the red blood cells and improve the metabolism of the red blood cells.

关 键 词：旋转磁场 红细胞 NA^+-K^+-ATP酶 CA^2+-MG^2+-ATP酶 

分 类 号：R446.112[医药卫生—诊断学]