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机构地区:[1]广东医学院附属医院急救中心,广东湛江524001 [2]广东医学院附属医院血透中心,广东湛江524001
出 处:《海南医学院学报》2010年第6期807-809,共3页Journal of Hainan Medical University
基 金:海南医学院科研基金资助学报项目(0020100232)~~
摘 要:目的:探讨应用血液灌流(hemoperfusion,HP)抢救重度急性有机磷农药中毒(acute organicpesticide poisoning,AOPP)患者的疗效及护理。方法:对我院自2000年1月~2006年1月收治的76例重度急性有机磷中毒患者随机分为血液灌流组50例(HP组),非血液灌流组26例(对照组),两组患者均予阿托品、解磷定等综合治疗,HP组在此基础上加用血液灌流或血液灌流+血液透析治疗,比较两组疗效。结果:HP组平均住院时间,胆碱脂酶活力恢复时间均短于对照组(P<0.05)。HP组病死率明显低于对照组(P<0.05)。结论:血液灌流或血液灌流+血液透析能有效清除体内的毒物,提高抢救成功率,在治疗时加强血液灌流的各项护理工作,是顺利进行血液灌流的关键。Objective: To explore the effects of hemoperfusion(HP) on acute organophosphorus pesticide poisoning(AOPP),and the patients' nursing.Methods: A total of 76 AOPP patients who were admitted to our hospital during January 2000 to January 2006 were randomly divide into HP group(50 cases and non-HP group(26 cases).Both groups were given atropine and pralidoxime comprehensive therapy;the HP group was also given an extra treatment of HP and hemodialysis.Therapeutic effects of the two groups were compared.Results: Hospital stay and cholinesterase rejuvenation time of the HP group was significant shorter than that of the non-HP group(P0.05);and the mortality of the HP group was lower than that of the latter group(P0.05).Conclusions: HP or HP plus hemodialysis therapy can raise the rescue rate by eliminating toxicology in the body effectively;specifically the ancillary nursing work is the key to successful rescue.
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