丝涤交织人造血管的研究  

Study on a silk-dacron interwoven vascular prosthesis

作　　者：陈福真[1] 冯友贤 杨珏[1] 符伟国[1] 徐欣[1] 陈稼 薛瑛 黄士通[3] 

机构地区：[1]上海医科大学附属中山医院血管外科,200032 [2]上海丝绸科学研究所 [3]上海医科大学附属中山医院心研所病理科

出　　处：《中华实验外科杂志》1999年第1期30-31,共2页Chinese Journal of Experimental Surgery

摘　　要：目的研制新型真丝涤纶交织人造血管。方法采用38杂杂种犬，麻醉后将直径8～10mm，长度3O～50mm直型丝涤人造血管移植于胸主或腹主动脉并与聚四氟乙烯管作对照。术后按要求观察移植物通畅度、内膜生长情况、生物相容性，细胞毒反应等。结果移植血管通畅率为35／38（921％），移植后一月可完整形成新生的内膜和外膜，细胞毒性测试表明无毒性反应。结论新型丝涤交织人造血管是一种较理想的血管代用品，值得在临床推广使用。Objetive In order to develop new vascular prostheses, a silk-dacron interwoven prosthesis was studied. Method Straight segments 8 ～10mm in diameter and 30～50 mm in length were inserted into the thoracic or abdomianl aorta of 38 mongrel dogs. Studies included patency, intima formation, biocompatibility, cytotoxicity, etc. Result The patency rate of vessel graft was 92.1 % (35/38) on angiography. A new intima and adventitia were completely formed at 1 month post-grafting. There was good biocompatibility and no cytotoxic reactions were observed. Conclusion This new silk-dacron interwoven graft is a relatively good vascular prosthesis and can be recommended widely for clinical application.

关 键 词：人造血管 血管移植 真丝涤纶交织 

分 类 号：R622.4[医药卫生—整形外科] R318.11[医药卫生—外科学]