辽宁省农村地区女性高血压人群血脂异常的流行病学调查  

Prevalence of Dyslipidemia among the Hypertensive Female Adults in Fu-xin of Liaoning Province

作　　者：董小英[1] 张心刚[2] 孙兆青[2] 郑黎强[2] 孙英贤[1] 

机构地区：[1]中国医科大学附属第一医院心内科,辽宁省沈阳市110001 [2]中国医科大学附属第二医院心内科,辽宁省沈阳市110004

出　　处：《中国动脉硬化杂志》2010年第4期325-327,共3页Chinese Journal of Arteriosclerosis

基　　金：辽宁省科技攻关重点项目(2003225003)

摘　　要：目的调查辽宁省农村地区女性高血压人群血脂异常的流行病学特征,为农村地区女性人群血脂异常的防治提供依据。方法采用横断面流行病学调查方法于2004年至2006年对辽宁省阜新县农村地区3607名年龄≥35岁患原发性高血压的女性常住人群(≥5年)进行血脂异常状况调查,根据美国胆固醇教育计划成人治疗组第三次报告指南(ATPⅢ)标准对血脂异常情况进行诊断。结果在辽宁省农村地区女性高血压人群中,总胆固醇边缘升高和升高的异常率分别为36.2%和18.2%,高密度脂蛋白胆固醇降低的异常率为7.5%,低密度脂蛋白胆固醇边缘升高、升高和极高的异常率分别为17.2%、3.9%和1.0%,甘油三酯边缘升高、升高和极高的异常率分别为17.6%、20.0%和1.9%。总胆固醇边缘升高和升高的异常率均表现出随着年龄增长而增加(P<0.001),高密度脂蛋白胆固醇降低的异常率随着年龄增长而降低(P<0.001)。结论辽宁省阜新农村地区女性高血压人群血脂异常更明显,应对该人群进行代谢性疾病的评价及综合性干预,以预防心脑血管疾病的发生。Aim To investigate the current epidemiological characteristics of dyslipidemia among rural hypertensive female adults in Liaoning province and to provide scientific basis for the prevention and treatment of dyslipoproteinemia in China. Methods A cross-sectional survey was conducted during 2004～2006 through a cluster multistage sampling to a resident group of 3 607 individuals with hypertension,aged ≥35 years,in the countryside of Liaoning,China. Serum lipids levels were proposed by National Cholesterol Education Program Adult Treatment Panel Ⅲ. Results Of the study population 36.2% had borderline high total cholesterol （TC）,18.2% had high TC; and 7.5% had low high-density lipoprotein cholesterol （HDLC）; The population with borderline high,high,and very high low-density lipoprotein cholesterol （LDLC） was 17.2%,3.9% and 1.0%,respectively; In addition,17.6% had borderline high triglycerides （TG）,20.0% had high TG and 1.9% had very high TG. The age-specific prevalence of borderline high and high TC increased with age （P〈0.001）. The prevalence decreased from 35 years old in HDLC （P〈0.001）. Conclusion The prevalence of dyslipidemia was relatively high among rural female hypertensive patients in Liaoning province. It is very important to prevent and control dyslipidemia,so as to prevent these people from cerebrovascular diseases.

关 键 词：高血压 血脂异常 总胆固醇 低密度脂蛋白胆固醇 高密度脂蛋白胆固醇 甘油三酯 

分 类 号：R5[医药卫生—内科学]