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作 者:冀飞[1] 陈艾婷[1] 赵阳[1] 刘兴健[1] 周其有[1]
机构地区:[1]解放军总医院耳鼻咽喉-头颈外科解放军总医院耳鼻咽喉科研究所,北京100853
出 处:《临床耳鼻咽喉头颈外科杂志》2010年第10期447-449,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基 金:模式识别国家重点实验室开放课题(No:08-3-1)
摘 要:目的:分析比较耳蜗电图和ABR测试在听神经病(AN)诊断中的作用。方法:AN组为AN患者16例(32耳),对照组为感音神经性听力损失患者20例(26耳)。对2组受试者行交替极性短声刺激耳蜗电图和ABR测试。分别观测AN组和对照组的波形,并进行以下对比:①比较AN组患者的ABR和耳蜗电图波形引出率;②比较AN组与对照组耳蜗电图的复合动作电位(CAP)潜伏期和绝对幅度,以及总和电位(SP)与CAP的幅度比值。结果:AN组32耳中有25耳引出-SP或CAP,耳蜗电图总体引出率为78.1%。AN组的CAP潜伏期短于对照组(P<0.05),CAP绝对幅度低于对照组(P<0.05),-SP/CAP幅度比值高于对照组(P<0.01)。AN组仅5耳引出不完整的ABR波形,引出率为15.6%,且波形分化较差。ABR引出率明显低于耳蜗电图(P<0.01)。对照组全部引出分化良好的耳蜗电图和ABR波形。结论:耳蜗电图和ABR在AN的诊断中各自发挥重要作用。AN患者听觉信息的时间整合作用受到损害而强度感受机制受影响较小。Objective:To analyze and compare the clinical application of alternating click evoked electrocochleography(ECochG) and auditory brainstem response(ABR) in the diagnosis of auditory neuropathy(AN))subjects.Method:ECochGs and ABRs were recorded in 16 patients(32 ears) with AN /AD as AN group and 20 patients(26 ears) with sensorineural hearing loss(SNHL) as control group.Test stimuli were alternating polarity clicks.①To compare the occurrence rate of ECochGs and ABRs in AN patients.②To compare the peak latency of CAPs,absolute amplitude of CAPs,and amplitude ratios of-SP and CAP between AN group and control group.Result:ECochGs(-SPs or CAPs) presented in 78.1%(25 among 32 ears) of AN patients.CAPs latency of AN group was shorter than control group(P〈0.05),CAP absolute amplitude of AN group was lower than normal group(P〈0.05),while-SP/ CAP was higher than control group(P〈0.01).Deformed ABRs presented in only 5 ears among 32 tested AN ears,while relative good ABR waveforms were evoked in control group.The occurrence rate of ABRs(15.6%) was significantly lower than that of ECochGs in AN patients(P〈0.01).Conclusion:Both ECochGs and ABRs play important role in the diagnosis of AN.The capacity of temporal processing is significantly impaired while the intensity perception related capability is intact in AN patients.
关 键 词:前庭耳蜗神经疾病 诱发电位 耳蜗电图 听觉 脑干 听力损失 感音神经性
分 类 号:R764.3[医药卫生—耳鼻咽喉科]
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