豚鼠前庭下神经及三叉神经下颌支部分传入神经切断对声诱发咬肌反射的影响  

Effect of inferior vestibular and part of mandibular branch of trigeminal neurotomy on sound-induced masseter reflex potentials

作　　者：孙伟[1,2] 孔维佳[1] 李丹[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院耳鼻咽喉科,武汉430022 [2]解放军第209医院耳鼻咽喉科,黑龙江牡丹江157000

出　　处：《临床耳鼻咽喉头颈外科杂志》2010年第10期466-469,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:研究麻醉豚鼠前庭下神经及三叉神经下颌支部分传入神经切断对声诱发咬肌反射的影响。方法:20只豚鼠随机分成4组,正常对照组5只,单侧前庭下神经切断组5只,单侧下牙槽神经切断组5只,单侧耳颞神经切断组5只。4组动物分别进行Click声刺激诱发的咬肌反射检测。结果:正常对照组声诱发咬肌反射电位的负波(NP)阈值为(90.00±8.16)dBnHL。100、90、80、70 dBnHL单侧声刺激,同侧记录咬肌反射NP的引出率分别为100%、70%、40%、0。100、90、80 dBnHL单侧声刺激咬肌反射NP潜伏期分别为(6.55±0.25)ms、(6.61±0.16)ms、(6.70±0.13)ms。不同刺激强度,咬肌反射NP的潜伏期无明显差异(P>0.05)。单侧前庭下神经切断,术侧声诱发的咬肌反射消失。单侧下牙槽神经及耳颞神经切断组,术侧咬肌反射存在,NP的阈值、潜伏期与正常对照组无明显差异(P>0.05)。结论:声诱发的咬肌反射是前庭起源,不受三叉神经下颌支耳颞神经及下牙槽神经传入纤维的影响。Objective：To evaluate the influence of inferior vestibular and part of mandibular branch of trigeminal neurotomy on sound-induced masseter reflex potentials.Method： Twenty guinea pigs were randomly divided into four groups,including 5 normal control guinea pigs,5 received unilateral inferior vestibular neurotomy,5 received unilateral inferior alveolar nerve neurotomy,and 5 received auriculotemporal nerve neurotomy.Click sound-induced masseter reflex potentials were recorded in four groups,respectively.Result：The thresholds of negative peak（NP） of click sound-induced masseter reflex potentials in normal control group were（90.00±8.16）dBnHL.The response rates of the NP of the masseter reflex potentials using 100,90,80 and 70 dBnHL monaural acoustic stimulation with unilateral recording were 100%,70%,40% and 0,respectively.The mean latencies of the NP were（6.55±0.25）ms,（6.61±0.16）ms and（6.70±0.13）ms,when elicited by 100,90 and 80 dBnHL acoustic stimulation respectively.There was no significant difference between the stimulus intensity and the mean latency of the NP（P〉0.05）.Negative peak of click sound-induced masseter reflex potentials was not observed in the inferior vestibular neurotomy group.The NP was preserved in the inferior alveolar nerve and auriculotemporal nerve neurotomy groups.There were no significant difference of the mean thresholds and latencies of NP between normal control group and inferior alveolar nerve and auriculotemporal nerve neurotomy group（P〉0.05）.Conclusion： Click sound-induced masseter reflex potentials orininates from vestibular afferents.Afferent of inferior alveolar nerve and auriculotemporal nerve can not influence the vestibular evoked masseter reflex potentials.

关 键 词：前庭 三叉神经 声诱发咬肌反射电位 

分 类 号：R762[医药卫生—耳鼻咽喉科]