60例子宫内膜异位症药物治疗的比较  

Effects of drugs in the treatment of 60 cases with endometriosis

作　　者：陈文慧[1] 林建[1] 

机构地区：[1]广东省茂名市人民医院,525000

出　　处：《中国医学创新》2010年第19期20-21,共2页Medical Innovation of China

摘　　要：目的 观察子宫内膜异位症患者用小剂量米非司酮联合孕三烯酮治疗以及单纯用孕三烯酮或达那唑治疗的临床效果、不良反应.方法 将60例确诊的子宫内膜异位症患者随机分为3组治疗：A组小剂量米非司酮加孕三烯酮治疗（26例）,B组单纯服孕三烯酮胶囊（20例）,C组用达那唑口服治疗（14例）.对比分析各组的治疗总有效率、不良反应.结果 A组治疗较B、C组总有效率明显增高,而不良反应明显减少,差异有统计学意义（P＜0.05）.结论 小剂量米非司酮联合孕三烯酮治疗子宫内膜异位症对减少月经量、减轻痛经症状好,而肝脏损害及出现痤疮等副反应少,其方法优于单纯用孕三烯酮或达那唑治疗,值得推广.Objective To observe the different clinical effects and harmful reactions on the endometriosis （EMS） patients who were treated by little dosage mifepristone combining with gestrinone or purely treated by gestrinone or danasol. Methods A total of 60 cases diagnosed EMS patients were randomly divided into 3 groups： The patients in group A were treated by little dosage mifepristone combining with gestrinone （26 cases） ; patients in group B were only treated by gestrinone （20 cases） and patients in group C were treated by danazol （ 14 cases）. The total efficacies and harmful reactions in different groups had been compared. Results The efficacy in group A was obviously higher than that in group B or C and the harmful reactions were absolutely decreased. The differences had statistical significance （ P 〈 0.05 ）. Conclusion The little dosage mifepristone combined with gestriuone used to treat the patient with EMS can decrease the amount of menses, relieve the degree of dysmenorrheal and has seldom damage to liver and without acne appeared, which is better than the only use of gestrinone or danazol. Therefore, it is valuable for popularization.

关 键 词：子宫内膜异位症 米非司酮 孕三烯酮 达那唑 

分 类 号：R711.71[医药卫生—妇产科学]