脂肝清对急性血淤模型大鼠血液流变学的影响  

Effects of Zhiganqing on Hemorheology in Acute Blood-stasis Model Rats

作　　者：段卫华[1] 李玉红[1] 

机构地区：[1]天津中医药大学,天津300193

出　　处：《时珍国医国药》2010年第6期1352-1353,共2页Lishizhen Medicine and Materia Medica Research

基　　金：国际科技合作项目(No.2009DFA31070)

摘　　要：目的观察脂肝清对急性血淤模型大鼠血液流变学的影响,为临床用药提供实验依据。方法大鼠灌胃相应的蒸馏水或药物14 d后,皮下注射0.1%盐酸肾上腺素0.9 mg/kg加冰浴造成急性血淤模型,观察脂肝清对此模型的影响。结果脂肝清能够降低此模型在230 I/S、115 I/S、46 I/S、23 I/S、11.5 I/S、5.75 I/S切变率时的全血粘度,降低其血浆黏度、血浆纤维蛋白原含量,减慢血沉,降低红细胞压积。结论脂肝清具有改善急性血淤模型大鼠血液流变学的作用。Objective To observe the effects of Zhiganqing,a kind of Chinese drug,hemorheology in acute blood-stasis model rats.Methods The rats were subcutaneous injected with epinephrine and treated with ice-water bath to create acute blood-stasis model after treated with distilled water or drugs for 14 days.Results Zhiganqing lowered blood viscosity,plasma viscosity,plasma fibrinogen and volume of packed red cells and slowed down blood sedimentation rate.Conclusion Zhiganqing can improve hemorheology in acute blood stasis model rats.

关 键 词：脂肝清 血液流变学 大鼠 

分 类 号：R285.5[医药卫生—中药学]