手性三齿席夫碱金属络合物催化的不对称反应  

Asymmetric Reactions Catalyzed by Chiral Tridentate Schiff Base-Metal Complexes

作　　者：林丽丽[1] 刘小华[1] 冯小明[1] 

机构地区：[1]四川大学化学学院,成都610064

出　　处：《化学进展》2010年第7期1353-1361,共9页Progress in Chemistry

基　　金：国家自然科学基金项目(No.20732003)资助

摘　　要：各种手性三齿席夫碱与金属(钛,铬,钒,铁,铜,铝)形成的络合物,在催化醛的硅腈化、Diels-Alder、Aldol、杂ene、硫化物的氧化等不对称反应中具有良好的催化活性和对映选择性;其中一些催化体系已成功地应用于天然产物的全合成中,该研究取得了系统性的研究成果。本文综述了手性三齿席夫碱金属络合物在不对称催化反应中的研究进展,同时,探讨了催化剂结构和反应条件对其催化活性和对映选择性的影响。The chiral tridentate Schiff bases, which derived from various chiral amino alcohols and salicylaldehyde derivatives, complexed with metals, such as Ti, Cr, V, Cu, Fe and AI, have shown catalytic ability in many asymmetric reactions. Especially in asymmetric trimethylsilylcyanation of aldehydes, Diels-Alder reaction, aldol reaction, hetero-ene reaction and sulfide oxidation reaction, systematic work has been reported. The development of the work was described in this review, meanwhile, the catalytic activity and enantioselectivity infuenced by the structure of catalyst and reaction condition were also discussed.

关 键 词：三齿席夫碱 金属络合物 手性 不对称催化 

分 类 号：O621.34[理学—有机化学]