肺部真菌感染54例临床分析  

54 cases of pulmonary fungal infection

作　　者：赖月平[1] 邱志坚[1] 

机构地区：[1]四川省泸州市人民医院,646000

出　　处：《重庆医学》2010年第13期1691-1692,共2页Chongqing medicine

摘　　要：目的探讨肺部真菌感染的易患因素、临床特征、治疗和预后。方法应用回顾性调查的方法对本院2005-2009年收治54例住院患者肺部真菌感染患者临床资料进行分析,诊断标准采用中华医学会《侵袭性肺部真菌感染的诊断标准与治疗原则》（草案）。结果 95%（51/54）的病例患有基础疾病,其中以慢性阻塞性肺疾病（COPD）、系统性红斑狼疮、白血病和慢性肾病为多见;肿瘤性疾病也占有重要位置;原发性肺部真菌感染少见。肺部真菌感染的临床表现无特异性,X线表现以支气管肺炎多见（59.3%）。病原菌主要以酵母菌属为主（79.5%）,早期诊断困难。肺部真菌感染病死率较高。结论多种疾病易继发肺部真菌感染,早期诊断较困难。其临床表现特异性少,发病呈上升趋势,病死率高,应引起临床高度重视。Objective To find out the clinical features, therapeutic outcome, prognosis and the major predisposing cllseases ot pulmonary fungal infection（PFI）. Methods 54 cases with PFI in local hospital during 2005 to 2009 were retrospectivelyanaly ana- lyzed. Results Various predisposing diseases were found in 95% of total cases, among them,COPD, systemic lupus erythromatus （SLE） ,leukemia and chronic renal disease were main predisposing diseases. Primary pulmonaryfungal infection was rare. All the clinical manifestations of PFI were not specific, reontgenographic features showed mainly bronchitis type（59.3 % ）. Monilia （Candi- da） was ranked the first pathogen （79.5 %）. The mortality of PIF was high. Conclusion PFI is an important cause of the secondary infection in many diseases. The clinical features of PFI is non-specific and the morbidity is rising. Clinicians should pay more atten- tion to it.

关 键 词：肺 真菌感染 临床分析 

分 类 号：R563.1[医药卫生—呼吸系统] R519[医药卫生—内科学]