神经外科围手术期抗菌药物应用调查分析  

Survey on utilization of antimicrobials during neurosurgical perioperation period

作　　者：任会琴[1] 步金梅[1] 吴剑涓[1] 

机构地区：[1]天津市环湖医院,天津300060

出　　处：《天津药学》2010年第3期42-45,共4页Tianjin Pharmacy

摘　　要：目的:调查本院神经外科围手术期抗菌药物应用情况,以便有针对性地加强药物合理使用的管理。方法:回顾性调查2008年2—4月本院神经外科择期手术142例出院病例,对其中手术路径、手术持续时间、切口愈合,预防性应用抗菌药物品种、联合用药、用药时机、持续用药时间进行统计分析。结果:抗菌药物术前用药占99.29%,用药时机在术前0.5～2h。术前以单品为主,占92.69%,主要品种为糖肽类;术后单品种用药占45.07%,二联用药占52.82%;术后用药品种以β-内酰胺类为主,其次是氨基糖苷类和氟喹诺酮类。结论:本院神经外科手术患者使用抗菌药物存在一些问题,有待加强规范化使用的管理。Objective：To supply suggestions for better management of drug usage via investigation into the usage of antibacterial drugs during neurosurgical perioperation period in our hospital.Method：142 randomly selected discharged patients＇ records from February to April 2008 were investigated.Statistical analysis is conducted on operation pathway,operation duration,wound healing,varieties of antibacterials for prophylactic use,drug combination,medication timing and continuous medication time.Results：The antibacterials,mainly glycopeptides,were used within 0.5 to 2 hours before operation and the application ratio accounted for 99.29% of the total cases.Single and multiple drug application ratio was 45.07% and 52.82% respectively for post-operation medication.β-lactam,aminoglycosides and fluoroquinolones were the mainly used.Conclusions：Antibacterials usage for neurosurgical operation patients still has some problems in our hospital,so it is very important to strengthen the standardized administration.

关 键 词：围术期 抗菌药物 合理使用 

分 类 号：R97[医药卫生—药品]