老年陈旧性心肌梗死介入治疗后心肌标志物水平变化分析  

Changes of Serum Cardiac Markers after Coronary Stent Implantation in Elderly Patients with Old Myocardial Infarction

作　　者：乔树洲[1] 张明旭[1] 刘丽华[1] 王梅[1] 黄慧[1] 白志冬[1] 任艳红[1] 

机构地区：[1]兰州军区兰州总医院干一科,甘肃省兰州市730050

出　　处：《中国全科医学》2010年第17期1912-1913,共2页Chinese General Practice

摘　　要：目的探讨陈旧性心肌梗死患者冠状动脉内支架植入术(CS)后心肌标志物的水平变化及临床意义。方法对比分析陈旧性心肌梗死行CS治疗后血浆肌酸激酶(CK)、肌酸激酶-同工酶(CK-MB)、肌钙蛋白(cTn-T)水平升高者与未升高患者术后心力衰竭的发生率。结果 CS术后CK、CK-MB和cTn-T水平升高患者术后1、2年心功能衰竭发生率为1/24和9/24,较未升高组(1/18和3/18)明显升高,差异有统计学意义(P<0.05)。结论陈旧性心肌梗死CS术后心肌标志物水平升高,标志着心肌再灌注成功的同时,既往变性坏死心肌细胞释放出一定量的心肌标志物,通过这些心肌标志物定量判断心功能不全的发生,为预后提供依据。Objective To study changes of serum cardiac markers after coronary stent implantation （CS） in elderly patients with old myocardial infarction （OMI） and its clinical values.Methods The laboratory indicators including serum creatine kinase （CK）,creatine kinase isoenzyme （CK-MB）,and cTn-T（cTn）levels were tested before CS and 12 hours after CS in the elderly patients with OMI in our hospital from May,2002 to May,2006.The incidences of heart failure were compared between patients with increased indicators and those without the increase of these indicators.Results CK,CK-MB,and cTn level remarkably increased in 24 patients but was not significantly increased in 18 patients after CS.The incidence of heart failure was significantly higher in the indicator-increased group than in non-increased group（P〈0.05）.Conclusion Elevation of serum cardiac markers can be used to predict the future risk of heart failure.

关 键 词：血管成形术 经腔 经皮冠状动脉 肌酸激酶 肌钙蛋白 

分 类 号：R541.4[医药卫生—心血管疾病]