冠状动脉病变程度与维吾尔族空腹血糖切点关系  

Relationship of cut-point of fasting glucose with the extent and severity of coronary artery disease in Uygur

作　　者：张铭晖[1] 朱筠[1] 

机构地区：[1]新疆医科大学第一附属医院内分泌科,乌鲁木齐市830054

出　　处：《中华实用诊断与治疗杂志》2010年第7期644-646,共3页Journal of Chinese Practical Diagnosis and Therapy

基　　金：新疆医科大学创新基金;新疆维吾尔自治区重点学科(内科学)建设经费(2004-2008)

摘　　要：目的：分析维吾尔族不同空腹血糖水平与冠状动脉病变程度的关系,探讨空腹血糖切点下调的意义。方法：回顾性分析321例拟诊冠心病于本院行冠状动脉造影的维吾尔族患者临床资料,依据空腹血糖水平分为4组：组1为空腹血糖〈5.6 mmol/L;组2为5.6 mmol/L≤空腹血糖〈6.1 mmol/L;组3为6.1 mmol/L≤空腹血糖〈7.0mmol/L;组4为空腹血糖≥7.0 mmol/L）,对不同空腹血糖下冠状动脉病变程度（病变支数,冠状动脉积分）进行分析。结果：校正年龄、性别、血脂紊乱等因素后,与组1比较,组2冠状动脉病变支数增加,差异有统计学意义（P〈0.05）,组3冠状动脉病变支数及冠状动脉病变总积分均明显增加,差异均有统计学意义（P〈0.01）。结论：维吾尔族冠心病高危人群的冠状动脉病变程度随空腹血糖水平升高逐步加重,冠状动脉发生病变的风险自空腹血糖5.6~6.1 mmol/L阶段己开始明显增加。将空腹血糖的下限调整到5.6 mmol/L对预防心血管病变具有重要意义。Objective To study the significance of lowering the cut-point value of fasting glucose by studying the extent and severity of coronary artery disease with different fasting glucose levels.Methods The data of 321 patients receiving coronary angiography were analyzed retrospectively,and divided into 4 groups according to the level of fasting glucose.The extent and severity of coronary artery disease with different fasting glucose levels were studied.Results After correcting the age,sex and other influencing factors,the number of diseased vessels increased in group 2（P0.05）,and the number of vessels and the coronary artery disease Gensini cumulative index increased in group 3（P0.01） compared with group 1,respectively.Conclusion In Uygur,the extent and severity of angiographic coronary artery disease increase with the increase of fasting glucose.The risk of angiographic coronary artery disease elevates significantly with fasting glucose at 5.6 to 6.0 mmol/L level.To lower the cut-point level of fasting glucose to 5.6 mmol/L is important to prevent cardiovascular disease.

关 键 词：冠状动脉病变 维吾尔族 空腹血糖受损 冠状动脉造影 

分 类 号：R543.3[医药卫生—心血管疾病]