大鼠冠根部牙髓体内成牙能力比较  

Study on the odontogenic capability of rat crown and root pulps in vivo

作　　者：雷港[1,2] 闫明[1,2] 俞艳[1,2] 于金华[1,2] 张光东[1,2] 

机构地区：[1]南京医科大学口腔医学研究所 [2]南京医科大学附属口腔医院牙体牙髓病科,南京210029

出　　处：《口腔生物医学》2010年第2期68-70,93,共4页Oral Biomedicine

基　　金：江苏省自然科学基金(BK2009346)

摘　　要：目的比较成年大鼠冠、根部牙髓分别接种于肾被膜下的成牙能力。方法无菌条件下分离8周龄SD大鼠切牙牙髓,将冠部与根部牙髓锐分离,分别植入大鼠肾被膜下,2周后进行组织学观察。结果冠部牙髓形成了包含釉质样组织和牙本质-牙髓复合体的牙齿样结构,与正常牙齿相似。而根部牙髓则形成了骨样牙本质结构。结论成年大鼠牙髓依然具有独立的牙齿发育的能力,冠髓和根髓的成牙能力不尽相同。Objective To investigate the odontogenic capacity of rat crown and root pulps by the allotransplantation in renal capsules. Methods Crown and root pulps were isolated from the incisors of the 8-weeks rats, then transplanted into renal capsules of rats. The recovered implants were analyzed by histology two weeks later. Results The crown pulp in the renal capsules formed the tooth- like mineralized tissues containing enamel-like tissue and dentine-pulp-like complex after the implantation. The morphology and arrangement of mineralized tissue were similar to normal tooth. Whereas retrieved root pulp in vivo generated the osteodentin-like structures. Conclusions Adult rat dental pulp still kept the capacity of odontogenesis. The odontogenic capacities of crown and root pulps were different.

关 键 词：牙髓 组织工程 异体移植 成牙能力 

分 类 号：R329-33[医药卫生—人体解剖和组织胚胎学]