室间隔缺损合并肺动脉高压的外科治疗  

Surgical treatment for ventricular septal defect with severe pulmonary hypertension

作　　者：廖成全[1] 姜月平[1] 陈翀[1] 万仁平[1] 

机构地区：[1]粤北人民医院心胸外科,广东韶关512026

出　　处：《中外医学研究》2010年第13期33-35,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的探讨基层医院室间隔缺损合并重度肺动脉高压（PH）的外科治疗方法。方法11例室间缺损合并肺动脉高压患者采用单向活瓣补片修补室间隔缺损，同时肺动脉内留置导管泵入前列腺素El（PGEI）；术后超声心动图动态监测分流情况，并比较术前术后肺动脉压（PAP）及血气分析指标变化。结果11例患者无一例死亡，术后2个月内单向活瓣关闭、分流消失；术后PAP明显下降，血气分析指标明显改善。结论单向活瓣补片及肺动脉置管泵入前列腺素E1（PGEI）能有效提高基层医院室间隔缺损合并肺动脉高压的治疗效果，增加围手术期安全性。Objective To evaluate the effective of surgical treatments on congenital heart defects with severe pulmonary hypertension （PH） in primary hospital. Methods 11 cases of ventrieular septal defect with pulmonary hypertension were treated with one - way valved patch repair of ventricular septal defect, and pulmonary artery catheter infusion of prostaglandin E1 （ PGE1 ） ; postoperative echocardiography dynamic monitoring of diversion, and to compare before and after operation pulmonary artery pressure （PAP） and arterial blood gas analysis were ob- served. Results No one cases of 11 patients died within 2 months after a one - way valve closed, shunt dlsappeared; postoperative PAP decreased significantly improved blood gas analysis. Conclusion One - way valved patch and the pulmonary artery catheter infusion of prostaglan- din E1 （PGE1） can effectively improve the primary hospital ventricular septal defect with pulmonary hypertension treatment, and increase the perioperative safety.

关 键 词：先天性心脏病 室间隔缺损 肺动脉高压 单向活瓣补片 前列腺素EI 

分 类 号：R654.2[医药卫生—外科学]