秦皇岛市大学生人体测量指标与丙氨酸氨基转移酶相关性研究  

Relationship between anthropometric parameters and alanine aminotransTerase in Qinhuangdao college students

作　　者：秦春梅[1] 王锐[1] 陆强[1] 张文丽[2] 玄续敏[1] 刘波[1] 刘晓丽[1] 马春明[1] 

机构地区：[1]河北省秦皇岛市第一医院内分泌科,066000 [2]河北省秦皇岛市第一医院CT室,066000

出　　处：《中华健康管理学杂志》2010年第3期145-148,共4页Chinese Journal of Health Management

摘　　要：目的探讨大学生人体测量指标与丙氨酸氨基转移酶（ALT）的关系。方法通过分层整群随机抽样的方法，选取秦皇岛市789名在校大学生（男性369例，女性420例）作为研究对象，测量身高、体重、腰围、臀围、血压和ALT，计算体质指数、腰围身高比和腰臀比。结果本研究共检出ALT升高大学生77例，其中男性60例（16．3％），女性17例（4．0％），男性检出率高于女性（P〈0．05）。男性ALT升高组各人体测量指标均高于ALT正常组（P〈0．05）；女性ALT升高组各人体测量指标与ALT正常组比较无统计学差异（P〉0．05）。男性各肥胖指标识别ALT升高的ROC曲线下面积均在0．8～0．9之间（P〈0．05），准确性中等。收缩压和舒张压识别ALT升高的曲线下面积在0．5～0．7之间（P〈0．05），准确性较低。女性各人体测量指标识别ALT升高的曲线下面积均在0．5—0．6之间（P〉0．05），准确性较低。结论男性大学生ALT升高比女性更为普遍。男性肥胖指标可作为识别ALT升高的有效指标，而女性效能较差。无论男女，血压识别ALT升高的效能均较差。Objective To investigate the correlation of anthropometric parameters with alanine aminotransferase （ALT） in Qinhuangdao college students. Methods A total of 789 subjects from two colleges in Qinhuangdao City （369 men and 420 women） were recruited using a cluster-stratified sampling method. Anthropometric measurements included height, body weight, waist circumference, hip circumference, blood pressure, and ALT. Body mass index, waist to height ratio, and waist to hip ratio were calculated. Results Elevated ALT was found in 16. 3% of male participants and 4. 0% of females （ P 〈 0. 05 ）. For males, those with elevated ALT showed significantly higher levels of anthropometric parameters （P 〈 0. 05 ）. In females, the levels of anthropometric parameters were similar between subjects with or without elevated ALT （P 〉 0. 05 ）. Receiver operating characteristic curve analysis also showed that obesity indices predicted elevated ALT only in men [ area under the curve： 0. 8-0. 9 （P 〈 0. 05 ） in men,0. 5-0. 6 （P 〉 0. 05） in women]. Blood pressure did not predict elevated ALT in both men and women （area under the curve： 0. 5-0. 7）. Conclusion Dender difference of obesity indices could be found in Qinhuangdao college students. Obesity indices may be independent predictors of elevated ALT in men. However, blood pressure seems not to be an independent predictor of elevated ALT.

关 键 词：肥胖 血压 丙氨酸转氨酶 

分 类 号：R589[医药卫生—内分泌]