内皮细胞的活化／损伤与炎症反应  

Activation/injury of the endothelial cells and the initiation and resolution of inflammation

作　　者：徐尤年[1] 马璞[1] 张曌[1] 张诗海[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院麻醉科,武汉430030

出　　处：《中国急救医学》2010年第6期552-554,共3页Chinese Journal of Critical Care Medicine

摘　　要：炎症研究通常以白细胞组织浸润为重点,多种细胞因子错综复杂地交织呈网状,以各种不同的方式作用于白细胞的同时,也在改变着血管内皮细胞的功能,而血管内皮细胞发生的变化也影响着炎症反应的发生、发展,因此,血管内皮细胞主动参与了炎症反应并在炎症反应过程中起着重要的调控作用.本文旨在对血管内皮细胞活化/损伤在炎症反应发生和消退中作用的研究进展做一简要综述.Inflammation is usually analyzed from the perspective of tissue - infiltrating leukocytes. Mediators that act on the leukocyte also act on the endothelium cells and vice versa. A wide variety changes in the properties of the endothelium greatly alter the process of the inflammatory response, thus the vascular endothelium cells at site of inflammation are active participants in and regulators of inflammatory process. This review describes the latest advance of the endothelium cell activation/injury in the initiation and resolution of inflammation.

关 键 词：血管内皮细胞 炎症 治疗 

分 类 号：R392[医药卫生—免疫学]