HPLC测定中药水煎液中人参皂苷Rg_1、Rb_1和三七皂苷R_1的含量  

Determination of Ginsenoside Rg_1,Rb_1 and Notoginsenoside R_1 in Traditional Chinese Medicine Decoction by HPLC

作　　者：陈有智[1] 张德莉[1] 李晓强[1] 李平[1] 魏琴[1] 

机构地区：[1]兰州大学第二医院,兰州730030

出　　处：《中国药师》2010年第7期975-977,共3页China Pharmacist

摘　　要：目的:建立中药水煎液中人参皂苷Rg_1、Rb_1和三七皂苷R_1的含量测定方法。方法:采用高效液相色谱法测定三七及复方丹参滴丸水煎液中有效成分含量。结果:三七及复方丹参滴丸水煎液中人参皂苷Rg_1、Rb_1及三七皂苷R_13种成分均达到良好分离,在测定范围内线性良好,回收率在99.2%～100.4%之间。结论:所建立的定量方法简便可行、重复性好,可用于含三七皂苷类成分的中药制剂的质量控制。Objective： To establish a method for simultaneous determining ginsenoside Rgl, Rb1 and notoginsenoside R1 in traditional Chinese medicine decoction. Method ： The effective components in decoction of radix et rhizoma notoginseng and compound dansen pill were determined by HPLC. Result： The resolution and the linearity were fine. The average recoveries of ginsenoside Rgl, Rbl and notoginsenoside Rl were between 99. 2% and 100. 4%. Conclusion： The method is simple ,feasible and repeatable,and is beneficial for quality control of these Chinese medicine preparations.

关 键 词：高效液相色谱法 人参皂苷RG1 人参皂苷RB1 三七皂苷R1 

分 类 号：R927.2[医药卫生—药学]