载银羟基磷灰石抗菌剂的研究和应用  

Reseach and Application of Ag-loaded Hydroxyapatite Antibacterial Agents

作　　者：蒋庆连[1] 田一光[1] 银德海[1] 兰云军[1] 

机构地区：[1]温州大学化学与材料工程学院,浙江温州325027

出　　处：《皮革与化工》2010年第3期13-17,共5页Leather And Chemicals

摘　　要：很多金属离子具有抗菌作用,其中银离子抗菌能力最强,抗菌谱广,对人体安全。羟基磷灰石(简称HA)的生物相容性及生物活性良好,热稳定性好。通过离子交换,将银离子负载在HA上,得到载银羟基磷灰石抗菌剂,应用在皮革的湿加工的后期和喷涂工序中,其适用范围比光催化型抗菌剂广,耐高温性能比其它无机载银抗菌剂好,是一种很有应用前景的无机抗菌剂。本文对载银羟基磷灰石抗菌剂的制备、抗菌机理、抗菌性能和应用进行了综述,并对存在的问题进行了探讨。Silver ion has the most strong antibacterial effects and a broad spectrum of antibacterial activity among many kinds of metal ions and is fairly safe to human body.Hydroxyapatite（HA） is excellent in biocompatibility,bioactivity and thermostability.Silver ion can be loaded into HA by means of ion-exchanging reaction to prepare Ag-loaded HA antibacterial agents.Applied in the late leather wet processing and the finishing processes.It has a wider range of applications than photocatalysts and is more thermostable than other kind of inorganic Ag-loaded antibacterial ones,and shows great promises for realistic application in the future.Aspects of Ag-loaded HA antibacterial agents,such as preparation,antibacterial mechanism,performances and applications,have been reviewed and some existing problems have been also discussed.

关 键 词：银 羟基磷灰石 抗菌剂 

分 类 号：S482.2[农业科学—农药学]