新生儿高胆红素血症的围产因素分析及磁共振检查  

The value of magnetic resonance imaging in the newborn with severe hyperbilirubinemia

作　　者：张平[1] 张怡[2] 吴武林[1] 陈蕾[1] 郝长胜[1] 

机构地区：[1]广东省深圳市龙岗中心医院,深圳518116 [2]湖南省中南大学湘雅医院,长沙410008

出　　处：《按摩与康复医学》2010年第18期26-27,共2页Chinese Manipulation and Rehabilitation Medicine

摘　　要：目的：了解新生儿高胆红素血症发生的围产因素,探讨磁共振（MR）检查在新生儿高胆红素血症中的作用.方法：回顾性分析45例高胆红素血症患儿临床及MR检查资料.结果：高胆红素血症的发生与早产、难产、窒息,产伤及使用催产素等有关系.45例高胆红素血症患儿,其中经临床、随访及MR证实新生儿胆红素脑病（NBE）共19例,NBE MR主要表现为在T1加权像可见苍白球对称性高信号,19例NBE中T1加权像苍白球高信号有16例,MR诊断价值：苍白球高信号敏感性为84.2%,特异性96.2%.结论：了解高胆红素血症的围产因素,及早干预,减少其发生率.MR检查在NBE早期诊断中有重要的价值.Objective：Understand the causes of neonate hyperbilirubinemia and peripartal factors and explore the value of magnetic resonance imaging in the newborn with severe hyperbilirubinemia. Methods;Clinical and magnetic resonance imaging features of 45 patients with Newborn severe hyperbilirubinemia were retrospectively analyzed. Resalts：The occurrence of hyperbilirubinemia are related with premature delivery,dystocia,asphyxia and use of oxytocin. There are 19 cases of neonatal bilirubin encephalopathy were confirmed by clinical follow--up and MRI in the 45 patients with Newborn severe hyperbilirubinemia. The main MRI presentation are abnormal increased signal intensity in the globus pallidus on T1-- weighted images. There are 16 cases of neonatal bilirubin encephalopathy with abnormal increased signal intensity in the globus paliidus on Tl -- weighted images in the 19 cases of neonatal bilirubin encephalopathy. MR1 Diagnosis： the sensitivity of globus pallidus high signal was 84. 2%, the specificity of globus pallidus high signal was 96.2%. Conclusion：In order to reduce the incidence of hyperbilirubinemia, we must understand the perinatal factors, early intervention. Magnetic resonance imaging has an important value in early diagnosis of NBE.

关 键 词：新生儿 高胆红素血症 围产因素 磁共振 

分 类 号：R714[医药卫生—妇产科学]