小剂量安定配合常规综合治疗对不稳定型心绞痛患者焦虑和cTnI的影响  

Effect of Low-dosage Diazepam Combined with Conventional Therapy on Anxiety and cTnI(troponin I) of Patients With Unstable Angina Pectoris(UAP)

作　　者：周意平 曾高峰[2] 

机构地区：[1]湖南省常宁市人民医院心内科,湖南衡阳421500 [2]南华大学第二附属医院心内科

出　　处：《南华大学学报（医学版）》2010年第4期561-562,共2页Journal of Nanhua University(Medical Edition)

摘　　要：目的观察小剂量安定配合常规综合治疗对不稳定型心绞痛(UAP)患者焦虑和cTnI(肌钙蛋白I)的影响。方法 60例UAP患者随机分为两组,对照组予以常规治疗,实验组在对照组的基础上加用小剂量安定治疗。观察两组治疗后第1天和15天时焦虑和cTnI的变化。结果两组1天时焦虑量表评分和cTnI浓度比较差异均无显著性(P>0.05),第15天时实验组焦虑量表评分(6.18±1.81,8.80±3.20分)和cTnI(0.15±0.06,0.30±0.08 ng/mL)浓度与对照组比较差异均有显著性(P<0.05)。结论小剂量安定可降低UAP患者焦虑和cTnI水平。Objective To observe effects of the diazepam of low dose combined with conventional therapy on anxiety and eTnI （ troponin I ） of patients with unstable angina pectoris （ UAP）. Methods 60 patients with UAP were randomly divided into two groups, control group received conventional treatment, and experimental group was given conventional treatment combined with a small dose of diazepam. The changes of anxiety and cTnI of two groups in the first day and fifteenth day were observed. Results Anxiety Scale score and cTnI concentration difference was not statistically significant （ P 〉 0.05 ） in the first day between the two groups. Anxiety scale score （ 6.18± 1.81 vs8.80 ±3.20 points ） and the levels of cTnI （0.15 ± 0.06 vs0.30 ± 0.08 ng / mL ） in the experimental group compared with the control group were significant different in the frfteenth day （ P 〈 0.05 ）. Conclusion Small dose of diazepam can reduce anxiety and cTnI levels in patients with UAP.

关 键 词：安定/治疗 心绞痛/不稳定型/治疗 焦虑 肌钙蛋白I 

分 类 号：R542[医药卫生—心血管疾病]