盐酸坦索罗辛单药治疗BPH 100例临床疗效观察  

Clinical observation on the therapeutic effect of the single therapy by Tamsulosin on 100 cases of benign prostatic hyperplasia

作　　者：罗杰鑫[1] 王卫峰[1] 赖俊彦[1] 

机构地区：[1]广东省东莞市人民医院普济分院泌尿外科,528014

出　　处：《中国实用医药》2010年第19期29-30,共2页China Practical Medicine

摘　　要：目的观察坦索罗辛单药治疗BPH(良性前列腺增生症)导致的LUTS(下尿路症状)的临床疗效。方法门诊选择100例BPH患者,随机分成2组,试验组50例,服用盐酸坦索罗辛0.2mg,1次/d;对照组50例,同时服用非那雄胺5.0mg,1次/d,盐酸坦索罗辛0.2mg,1次/d,观察药物治疗效果,主要是下尿路症状的改善。结果 1个月内下尿路症状的有效改善为试验组49例(98%),对照组48例(96%),两组差异无统计学意义(P>0.05)。两组患者IPSS均≤13分,QOL为(3±1)分,Qmax均≤18ml/s,残余尿量测定均≤40ml,服药前后比较并有统计学意义(P≤0.05)。结论盐酸坦索罗辛单药治疗BPH导致的LUTS的临床疗效满意。Objective To observe the therapentic effects of Tamsulosin for the treatment of benign prostatic hyperplasia （BPH）. Methods 100 outpatients with benign prostatic hyperplasia received were selec- rived, and were randomly divided into two groups. The experimental group （ 50 patients ） given Tamsulosin 0. 2 mg once a day , and the control group（50 patients） received Tamsulosin 0. 2 mg once a day and Finasteride 5 mg once a day both. Observed the efficiency of the drug therapy, mainly the improvement of the lower urinary tract symptoms（LUTS）. Results The lower urinary tract symptoms had improved effectively in 1 month, in the experimental group has 49 patients （98%） , and the control group has 48 （96%） , the difference between the ex-perimental group and the control group has no statistical significance（ P 〉 0. 05 ）. Both Of the two groups, the IPSS ≤13 points, the QOL is 3 ±1 points,Qmax≤18 ml/s, the residual urine volume≤40 ml, the difference has statistical significance（P ≤0. 05 ）. Concision The single therapy by Tamsulosin has a satisfactory clinical effect on the the treatment of LUTS caused by BPH.

关 键 词：良性前列腺增生症 下尿路症状 盐酸坦索罗辛 

分 类 号：R697.3[医药卫生—泌尿科学]