布托啡诺与芬太尼应用于术后静脉镇痛的临床观察  

Comparison of Clinical Effect of Venous Analgesia between Butorphanol Tartrateand Fentanyl

作　　者：刘江洪[1] 

机构地区：[1]中山大学附属东莞东华医院麻醉科,523110

出　　处：《中国实用医药》2010年第19期43-44,共2页China Practical Medicine

摘　　要：目的比较布托啡诺与芬太尼用于患者自控静脉镇痛(PCI)的临床价值。方法选择80例择期手术患者随机分为两组,N组(布托啡诺组:n=40):布托啡诺8mg、生理盐水加至100ml;F组(芬太尼组:n=40):芬太尼0.8mg、生理盐水加至100ml。选择负荷剂量加维持剂量即微泵连续给药方式行静脉镇痛(持续注药速度为2.0ml/h,单次PCA剂量为1ml,锁定时间30min)。结果 N组与F组相比,镇痛评分、镇静评分、恶心呕吐、尿潴留发生率均无显著差异性(P>0.05)。两组患者均无发生呼吸抑制。结论布托啡诺用于术后静脉镇痛,效果确切、不良反应少。Objective To compare the effects of patient2controlled intravenous analgesia（ PC I A） be- tw een butorphanol tartrate （ B T） and fentanyl. Methods Eghity patients were divided into t o group s at ran- dom. Group N was adm inistered with 8 mg of B T in 100 ml of saline, and Group F with 0. 8 rag of fentanyl in 100 ml of saline. The loading dosage and maintained do sage wereused as venous analgesia. Results There were no significant differences in visual ache sim ulation （ VA S） scoring, syrup tom s and urine retention be- tween B T and fentanyl without respiratory. Conclusion BT m ight be used as an analgetic agent after opera- tion with good effect.

关 键 词：术后静脉镇痛 布托啡诺 芬太尼 

分 类 号：R614[医药卫生—麻醉学]