低分子量肝素治疗不稳定性心绞痛临床观察  

CLINICAL EFFECT OF LOW MOLECULAR WEIGHT HEPARINS ON UNSTABLE ANGINA

作　　者：石玫[1] 李黎[1] 杨杰书[1] 李郁金[1] 

机构地区：[1]青岛医学院第二附属医院

出　　处：《河北医学》1999年第1期35-38,共4页Hebei Medicine

摘　　要：目的：观察低分子量肝素治疗不稳定性心绞痛的临床疗效；方法：将６４例不稳定性心绞痛患者随机分为常规治疗组（对照组）及常规治疗＋低分子量肝素组（治疗组），疗程为１周；结果：１周后总有效率：治疗组９３．７５％，对照组６８．７５％Ｐ＜０．０５；观察１２周治疗组无１例发生急性心肌梗塞，对照组３例发生（９．３８％）；治疗组未发现明显不良反应；结论：在常规疗法基础上加用低分子量肝素，能更有效地控制心绞痛发作。Objective:To observe the clinical therapeutic effect of low molecular weight heparins on patients with unstable angina pectoris.Methods:64 cases of unstable angina pectoris were randomly divided into 2 groups i.e. control group(conventional therapy)and observed group (Low molecular weight heparins plus conventional therapy).The course of treatment was one week.Results: The effective rate during the treatment was 93.75% in observed group and 78.13% in control group(p<0 05);Acute myocardical infarction was present in 3patients in control group and none in observed group during followed 12 weeks.There was no obvious adverse reaction in observed group.Conclusion:It was conseidred that lowmolecular weight heparins combined with conventional medication could control unstable angina more effectivly and reduce the incidence of AMI.

关 键 词：低分子量肝素 不稳定性 心绞痛 药物疗法 

分 类 号：R541.405[医药卫生—心血管疾病]