用于细胞核成像的2,7-BHVC双光子荧光探针  

Novel Two-photon Fluorescent Probe 2,7-BHVC for DNA Imaging

作　　者：贾鹏飞[1] 刘恒[1] 张元红[2] 刘鑫[2] 赵宁[2] 于晓强[2] 

机构地区：[1]兰州大学生命科学学院,兰州730000 [2]山东大学晶体材料国家重点实验室,济南250100

出　　处：《高等学校化学学报》2010年第6期1075-1077,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:50673053);教育部博士点基金(批准号:200807300014)资助

摘　　要：2,7-BHVC,a novel two-photon fluorescent probe for DNA with large two-photon excited fluorescence action cross sections,was synthesized and characterized.It emits weak two-photon fluorescence in aqueous solution while its two-photon fluorescence is strongly restored upon binding to DNA.The two-photon imaging in cell demonstrated that 2,7-BHVC can exactly label nuclear DNA.2,7-BHVC,a novel two-photon fluorescent probe for DNA with large two-photon excited fluorescence action cross sections,was synthesized and characterized.It emits weak two-photon fluorescence in aqueous solution while its two-photon fluorescence is strongly restored upon binding to DNA.The two-photon imaging in cell demonstrated that 2,7-BHVC can exactly label nuclear DNA.

关 键 词：双光子荧光探针 双光子荧光成像 DNA 

分 类 号：O644.17[理学—物理化学]