导管法测定大鼠肺循环血流量的研究  

STUDY ON CATHETER METHOD TO MEASURE BLOOD FLOW OF THE RAT PULMONARY CIRCUIT

作　　者：张诚[1] 李玉明 张秋实[1] 张游 

机构地区：[1]承德医学院低温生理研究室

出　　处：《承德医学院学报》1999年第1期1-3,共3页Journal of Chengde Medical University

基　　金：国家自然科学基金

摘　　要：目的：研究一种新的导管法测定肺循环血流量。方法：分离右侧颈外静脉，将塑料导管自右侧颈外静脉插入，经上腔静脉、右心房和右心室插入肺动脉。用上海产ＳＪ—４２型四导生理记录仪记录生理参数。结果：肺循环血流量可按公式ＱＰ＝ＭＰＡＰ·△ＱＭＰＡＰ－ＭＰＡＰ计算，式中△Ｑ是每分钟自肺循环流入容量测定计的血量，算得的ＱＰ＝２９．６２±３．７３ｍｌ／ｍｉｎ，在大鼠的肺循环血流量正常范围之内。Objective:To study a new catheter method to measure blood flow of the pulmonary circuit.Methods:The right vena jugularis externa was carefully dissected.A Plastic catheter was inserted from the right vena jugularis externa through the superior vena cava,right atrium,and right ventricle into the pulmonary artery.The physiological parameters were recorded with a 4 channel polygraph system,Model ST 42,manufactured in Shanghai,China.Blood flow of the pulmonary circuit was calculated according to the formula Qp=MPAP·△QMPAP-MPAP,where △Q is the volume of blood from the pulmonary artery into volumeter through the catheter per minute.Results:The calculated Q P=29,62±3.72ml/min.It was Within the limits of normal blood flow of the rat pulmonary circuit.Conclusion:The new self designed catheter method is exact and simple.

关 键 词：导管法 肺循环 血流量 

分 类 号：R331.37[医药卫生—人体生理学] R33－33[医药卫生—基础医学]