溶液环境对中药模拟体系陶瓷膜微滤过程的影响  

Effect of solution environments on ceramic membrane microfiltration of model system of Chinese medicines

作　　者：张连军[1] 陆瑾[1] 乐康[1] 付廷明[1] 郭立玮[1] 

机构地区：[1]南京中医药大学中药复方分离工程重点实验室,江苏南京210029

出　　处：《中国中药杂志》2010年第13期1691-1695,共5页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30873449)

摘　　要：目的:探讨不同"溶液环境"对中药模拟体系陶瓷膜微滤过程的影响。方法:以大豆蛋白、小檗碱二元体系为考察对象,以膜通量、小檗碱透过率、蛋白质截留率为指标,考察不同溶液环境对于膜过程的影响。结果:大豆蛋白在1 g.L-1的质量浓度下,膜通量最小,小檗碱的透过率随浓度增加略有降低;pH 4时膜通量最大,蛋白质截留率达99%,且小檗碱的透过率达到60%以上。结论:通过优化中药水提液的溶液环境,可以有效提高膜分离的效率,对于以蛋白质为主要膜污染物的溶液体系,调节pH至蛋白质的等电点附近时,膜分离效果较好。Objective： To investigate the effect of differents solution environments on the ceramic membrane microfiltration of model system of Chinese medicines.Method： Taking binary system of soybean protein-berberine as the research object,flux,transmittance of berberine and traping rate of protein as indexes,different solution environment on membrane process were investigated.Result： When the concentration of soybean protein was under 1 g·L-1,the membrane flux was minimum with the traping of berberine decreased slightly as the concentration increased.When pH was 4,the flux was maximum with the traping rate of protein was 99%,and the transmittance of berberine reached above 60%.Conclusion： The efficiency of membrane separation can be improved by optimizing the solution environment of water-extraction of chinese medicines.The efficiency of membrane separation is the best when adjust the pH to the isoelectric point of proteins for the proteins as the main pollutant in aqueous solution.

关 键 词：溶液环境 膜通量 模拟体系 蛋白质 小檗碱 

分 类 号：R283[医药卫生—中药学]