大鼠肝脏与胰腺再生间的相关性研究  

Research on the relationship between liver regeneration and pancreas regeneration

作　　者：刘泽刚[1] 徐明[1] 宋俊峰[1] 鲁建国[1] 

机构地区：[1]第四军医大学唐都医院,陕西西安710038

出　　处：《中国现代医学杂志》2010年第9期1293-1295,共3页China Journal of Modern Medicine

摘　　要：目的探讨肝脏与胰腺再生间的关联。方法 20只大鼠随机分成2组:15只SD大鼠戊巴比妥纳腹腔注射麻醉,切除58%的肝脏,对照组5只大鼠进行开关腹操作。饲养2周后,以10%的甲醛液灌注固定标本,取出每只大鼠的肝脏及胰腺,冰冻切片后进行免疫组化,观察大鼠的肝脏及胰腺再生情况。结果在饲养2周后,大鼠的肝脏及胰腺实验组均有不同程度的再生现象出现,对照组未观察到再生现象。结论肝脏和胰腺来源于同一胚胎层,它们的再生有着共同的交叉点。当肝脏处于再生活跃的情况下,诱导因子会同时引起胰腺的再生。【Objective】To investigate the relationship between liver regeneration and pancreas regeneration in rats.【Method】 20 SD rats were randomized into 4 groups：Establish 15 male SD rats model of liver regeneration by 58% hepatectomy.Control group5 SD rats only to switch abdominal operation.After 2 weeks,observe the phenomenon of the liver regeneration and pancreas regeneration by immunolhistochemistry,the regeneration phenomenon is not observed in control group.【Result】Liver and pancreas have different levels of regeneration phenomenon in experimental group.【Conclusion】 When the liver in the regeneration of active cases,the inducing factor will also cause regeneration of the pancreas

关 键 词：SD大鼠 肝脏 胰腺 再生 

分 类 号：R339.37[医药卫生—人体生理学]