复方木鸡冲剂对荷瘤小鼠淋巴细胞功能的影响  

Effects of Muji granules on lymphocyte functions in tumor-bearing mice

作　　者：孙杰[1] 郭连英[1] 谷学军[1] 邢嵘[1] 

机构地区：[1]大连医科大学病理生理学教研室,116044

出　　处：《实用医学杂志》2010年第12期2120-2122,共3页The Journal of Practical Medicine

摘　　要：目的:探讨复方木鸡冲剂对荷瘤小鼠淋巴功能的影响。方法:收集荷瘤小鼠的脾淋巴细胞,检测淋巴细胞的杀瘤活性、存活能力及分泌IL-2的情况,比较复方木鸡冲剂对荷瘤小鼠淋巴细胞的作用和影响。结果:与未给予复方木鸡冲剂处理组相比,复方木鸡冲剂能增强荷瘤小鼠淋巴细胞的杀瘤活性,提高淋巴细胞的存活能力,复方木鸡冲剂处理后淋巴细胞分泌IL-2明显增加。结论:复方木鸡冲剂能够增强荷瘤小鼠淋巴细胞的功能,刺激淋巴细胞分泌IL-2,以此影响机体的免疫功能和抗肿瘤。Objective To investigate the effects of compound Muji granules on lymphocyte functions in tumor-bearing mice. Methods Isolate spleen lymphocytes from normal mice, tumor-bearing mice, tumor-bearing mice treated with saline and tumor-bearing mice treated with compound Muji granule. And detect tumoricidal activities, survival abilities and IL-2 secretion of lymphocytes in each groups. Results Compared with control group, tumoricidal activity, lymphocyte survival rate and IL-2 secretion were significantly increased in compound Muji granules-treated group. Conclusion Compound Muji granules can enhance lymphocyte function and stimulate lymphocytes to express IL-2 in Tumor-bearing mice contributing to enhance anti-tumor abilities of mice.

关 键 词：白细胞介素2 复方木鸡冲剂 淋巴细胞 杀瘤活性 

分 类 号：R285.5[医药卫生—中药学]